A novel FeS cluster in Fe-only hydrogenases

被引：353

作者：

Nicolet, Y

Lemon, BJ

Fontecilla-Camps, JC

Peters, JW

机构：

[1] CEA, CNRS, Inst Biol Struct Jean Pierre Ebel, Cristallog & Cristallogenese Prot Lab, F-38027 Grenoble 1, France

[2] Utah State Univ, Dept Chem & Biochem, Logan, UT 84322 USA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2000年 / 25卷 / 03期

关键词：

D O I：

10.1016/S0968-0004(99)01536-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Many microorganisms can use molecular hydrogen as a source of electrons or generate it by reducing protons. These reactions are catalysed by metalloenzymes of two types: NiFe and Fe-only hydrogenases. Here, we review recent structural results concerning the latter, putting special emphasis on the characteristics of the active site.

引用

页码：138 / 143

页数：6

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