Neuroactive neurosteroids: dehydroepiandrosterone (DHEA) and DHEA sulphate

被引:17
作者
Baulieu, EE
机构
[1] INSERM U488, Hormone Lab, F-94276 Le Kremlin Bicetre, France
[2] Coll France, Le Kremlin Bicetre, France
关键词
ageing; dehydroepiandrosterone (DHEA); DHEA sulphate; gamma-aminobutyric acid (GABA) receptor A; neurosteroid; N-methyl-D-aspartate (NMDA) receptor;
D O I
10.1111/j.1651-2227.1999.tb14408.x
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Dehydroepiandrosterone (DHEA) and its sulphate ester (DHEAS) are neuroactive and are both imported into the brain from the circulation and produced in the nervous system. These neurosteroids have neurotrophic and excitatory effects, and further study is needed to delineate their physiological and pathological functions.
引用
收藏
页码:78 / 80
页数:3
相关论文
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