And Then There Were None: No Need for Pluripotency Factors to Induce Reprogramming

被引：10

作者：

Chou, Bin-Kuan ^{[1
,2
]}

Cheng, Linzhao ^{[1
,2
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Inst Cell Engn, Stem Cell Program, Baltimore, MD 21205 USA

[2] Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD 21205 USA

来源：

CELL STEM CELL | 2013年 / 13卷 / 03期

关键词：

EMBRYONIC STEM-CELLS; PRIMORDIAL GERM-CELLS; MOUSE SOMATIC-CELLS; LINEAGE SPECIFIERS; CULTURE;

D O I：

10.1016/j.stem.2013.08.004

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

While most factors used as reprogramming transgenes can be replaced by other means, Oct4 has remained essential until now. Three recent papers have now broken this barrier through the use of opposing lineage specifying transgenes and chemical modulation, thus signifying a milestone in advancing our understanding of pluripotency induction.

引用

页码：261 / 262

页数：2

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