The potential for elemental analysis in biotechnology

被引：59
作者：
Baranov, VI [1 ]
Quinn, ZA [1 ]
Bandura, DR [1 ]
Tanner, SD [1 ]
机构：
[1] MDS SCIEX, Concord, ON L4K 4V8, Canada
来源：
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY | 2002年 / 17卷 / 09期
关键词：
D O I：
10.1039/b201494g
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The ICP-MS brings particular attributes to the method that distinguishes it from organic mass spectrometry: relative insensitivity to concomitant organic or metallic species, equivalent sensitivity to all similarly-tagged complexes, inherent ability to provide absolute quantitation and linearity of response. All these positive features fit the requirements of modern-day biotechnology. In this work, the potential of ICP-MS is discussed in the context of several urgent problems of biotechnology including: the determination of the state of phosphorylation of proteins, quality control of biologically active materials and control of efficiency of cell line transfections.
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收藏
页码：1148 / 1152
页数：5
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