Injectable scaffolds: Preparation and application in dental and craniofacial regeneration

被引：183

作者：

Chang, Bei ^{[1
]}

Ahuja, Neelam ^{[1
]}

Ma, Chi ^{[1
]}

Liu, Xiaohua ^{[1
]}

机构：

[1] Texas A&M Univ, Coll Dent, Dept Biomed Sci, 3302 Gaston Ave, Dallas, TX 75246 USA

来源：

MATERIALS SCIENCE & ENGINEERING R-REPORTS | 2017年 / 111卷

关键词：

Scaffold; Injectable; Dental; Craniofacial; Tissue regeneration; POLY(ETHYLENE GLYCOL) HYDROGELS; HYALURONIC-ACID HYDROGEL; PULP STEM-CELLS; ASSEMBLING PEPTIDE HYDROGEL; CROSS-LINKING; CALCIUM-PHOSPHATE; BONE REGENERATION; POLYETHYLENE-GLYCOL; GROWTH-FACTOR; OSTEOGENIC DIFFERENTIATION;

D O I：

10.1016/j.mser.2016.11.001

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Injectable scaffolds are appealing for tissue regeneration because they offer many advantages over preformed scaffolds. This article provides a comprehensive review of the injectable scaffolds currently being investigated for dental and craniofacial tissue regeneration. First, we provide an overview of injectable scaffolding materials, including natural, synthetic, and composite biomaterials. Next, we discuss a variety of characteristic parameters and gelation mechanisms of the injectable scaffolds. The advanced injectable scaffolding systems developed in recent years are then illustrated. Furthermore, we summarize the applications of the injectable scaffolds for the regeneration of dental and craniofacial tissues that include pulp, dentin, periodontal ligament, temporomandibular joint, and alveolar bone. Finally, our perspectives on the injectable scaffolds for dental and craniofacial tissue regeneration are offered as signposts for the future advancement of this field. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：1 / 26

页数：26

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