Pathophysiology of writer's cramp

被引：86
作者：
Hallett, Mark [1 ]
机构：
[1] NINDS, Human Motor Control Sect, NIH, Bethesda, MD 20892 USA
来源：
HUMAN MOVEMENT SCIENCE | 2006年 / 25卷 / 4-5期
关键词：
hand; motor control; neuroimaging; plasticity; sensorimotor;
D O I：
10.1016/j.humov.2006.05.004
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Writer's cramp is a task-specific focal hand dystonia. The abnormality of task specificity is curious one and indicates that we need to learn more about the coupling of motor programs and their effectors. Writer's cramp appears to be triggered by spending much time writing by an individual with a fertile physiological substrate for producing the disorder. The fertile background, which is likely genetic, may be a decrease of inhibition, an increase of plasticity or an impairment in sensory function. Recent pathophysiological findings have implications for new therapies. Published by Elsevier B.V.
引用
收藏
页码：454 / 463
页数：10
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