Sevoflurane and anesthesia for neurosurgery - A review

被引:44
作者
Duffy, CM [1 ]
Matta, BF [1 ]
机构
[1] Addenbrookes Hosp, Dept Anesthesia, Cambridge CB2 2QQ, England
关键词
anesthetics; autoregulation; blood flow; brain; compound A; renal; sevoflurane; toxicity; volatile;
D O I
10.1097/00008506-200004000-00012
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
This review assesses the extent to which sevoflurane fulfills the requirements of the ideal inhalational agent for use in neuroanesthetic practice. Sevofturane's pharmacokinetic profile is outlined. Data from animal and human studies are used to discuss its effects on cerebral hemodynamics, central nervous system monitoring, and cardiovascular parameters. Where possible, sevoflurane is compared with isoflurane, currently considered the inhalational agent of choice in neuroanesthesia. Sevoflurane's potential for toxicity is reviewed.
引用
收藏
页码:128 / 140
页数:13
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