Acid-base homeostasis: Metabolic acidosis and metabolic alkalosis

被引：1
|
作者：
Dussol, Bertrand [1 ]
机构：
[1] Hop Conception, Ctr Nephrol & Transplantat Renale, F-13385 Marseille 05, France
来源：
NEPHROLOGIE & THERAPEUTIQUE | 2014年 / 10卷 / 04期
关键词：
Acid-base homeostasis; Proton; Buffers; Bicarbonate; Titratable acid; Ammonium; Metabolic acidosis; Metabolic alkalosis; ANION GAP;
D O I：
10.1016/j.nephro.2014.05.004
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Acid-base homeostasis ensured by the kidneys, which maintain the equilibrium between proton generation by cellular metabolism and proton excretion in urine. This requirement is lifesaving because of the protons' ability to bind to anionic proteins in the extracellular space, modifying their structure and functions. The kidneys also regenerate bicarbonates. The kidney is not the sole organ in charge of maintaining blood pH in a very narrow range; lungs are also involved since they allow a large amount of volatile acid generated by cellular respiration to be eliminated. (C) 2014 Association Societe de nephrologie. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：246 / 257
页数：12
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