Retinol-binding protein 4 is elevated and is associated with free testosterone and TSH in postmenopausal women.

被引：7

作者：

Guducu, N. ^{[1
]}

Gormus, U. ^{[2
]}

Kavak, Z. N. ^{[1
]}

Isci, H. ^{[1
]}

Yigiter, A. B. ^{[1
]}

Dunder, I. ^{[1
]}

机构：

[1] Istanbul Bilim Univ, Avrupa Hosp, Dept Obstet & Gynecol, TR-34692 Istanbul, Turkey

[2] Istanbul Bilim Univ, Avrupa Hosp, Dept Biochem, TR-34692 Istanbul, Turkey

来源：

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION | 2013年 / 36卷 / 10期

关键词：

Gonadotropin; postmenopausal women; retinol-binding protein 4; testosterone; TSH; POLYCYSTIC-OVARY-SYNDROME; INSULIN-RESISTANCE; ADIPOSE-TISSUE; VISCERAL FAT; SERUM RETINOL-BINDING-PROTEIN-4; OBESE; EXPRESSION; ADIPONECTIN; REDUCTION; HORMONES;

D O I：

10.3275/8948

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The aim of this study was to understand the relationship of retinol-binding protein 4 (RBP4) with hormonal and biochemical parameters in pre-and postmenopausal women. We included 69 postmenopausal women and 27 regularly menstruating premenopausal women. Postmenopausal women had statistically significantly higher RBP4 levels when compared to premenopausal women. RBP4 levels were negatively associated with free testosterone and positively as-sociated with thyroid stimulating hormone in postmenopausal women. In premenopausal women RBP4 was positively associated with body mass index. RBP4 levels were increased in postmenopausal women. Although the mechanism is not clear, these findings suggest that RBP4 has a role in the regulation of hormonal and metabolic parameters.

引用

页码：831 / 834

页数：4

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