SARS-CoV-2-specific IgG and NCP in vulnerable patients without symptoms

被引：0

作者：

Asti, Anna Lia ^{[1
]}

Lilleri, Daniele ^{[2
]}

Zelini, Paola ^{[3
]}

Gregorini, Marilena ^{[1
,4
]}

Morosini, Monica ^{[5
]}

Pattonieri, Eleonora Francesca ^{[1
]}

Grignano, Maria Antonietta ^{[1
]}

Libetta, Carmelo ^{[1
]}

Sepe, Vincenzo ^{[1
]}

Di Toro, Alessandro ^{[6
]}

Brazzelli, Valeria ^{[7
,8
]}

Rampino, Teresa ^{[1
]}

机构：

[1] Fdn & RCCS Policlin San Matteo, Unit Nephrol Dialysis & Transplantat, Pavia, Italy

[2] Fdn IRCCS Policlin San Matteo, Mol Virol Unit, Microbiol & Virol Dept, Pavia, Italy

[3] Fdn IRCCS Policlin San Matteo, Unit Obstet & Gynecol, Pavia, Italy

[4] Univ Pavia, Dept Internal Med & Therapeut, Pavia, Italy

[5] IRCCS Policlin San Matteo, Res Lab Lung Dis, Sect Cell Biol, Pavia, Italy

[6] Fdn IRCCS Policlin San Matteo, Transplant Res Area & Ctr Inherited Cardiovasc Di, Dept Med Sci & Infect Dis, Pavia, Italy

[7] IRCCS Policlin San Matteo Fdn, Inst Dermatol, Pavia, Italy

[8] Univ Pavia, Pavia, Italy

来源：

NEW MICROBIOLOGICA | 2022年 / 45卷 / 03期

关键词：

IgG anti SARS-CoV-2 (S); nucleic capsid protein (NCP); tumor nerosis factor alpha (TNF alpha); Interleukin-17 (IL-17); COVID-19; CARE;

D O I：

暂无

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Patients with severe COVID-19 both seroconvert earlier and develop higher concentrations of SARS-CoV-2-specific IgG than patients with mild symptoms. In this retrospective study we considered different categories of patients defined as "vulnerable" because affected by other pathologies, such as patients with genetic and cardiovascular diseases; patients with autoimmune dermatological disease; kidney and lung transplant patients, and pregnant women because the prevalence of Covid-19 infection during pregnancy is not known. This study was performed at IRCCS San Matteo Hospital in Pavia, North Italy, a zone considered at high risk during the COVID-19 pandemic from June to December 2020. None of the positive screened patients had symptoms of COVID-19 infection at the time of inclusion in this study.

引用

页码：213 / 218

页数：6

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