Pneumomediastinum in patients with AIDS: a case report and literature review

被引：9

作者：

Cheng, Wan-Ling ^{[1
,2
]}

Ko, Wen-Chien ^{[1
,2
,3
]}

Lee, Nan-Yao ^{[1
,2
]}

Chang, Chia-Ming ^{[1
,2
,3
]}

Lee, Ching-Chi ^{[1
,2
]}

Li, Ming-Chi ^{[1
,2
]}

Li, Chia-Wen ^{[1
,2
]}

机构：

[1] Natl Cheng Kung Univ, Hosp & Med Coll, Dept Internal Med, Div Infect Dis, Tainan 704, Taiwan

[2] Natl Cheng Kung Univ Hosp, Ctr Infect Control, Tainan 70428, Taiwan

[3] Natl Cheng Kung Univ, Coll Med, Dept Med, Tainan 70101, Taiwan

来源：

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES | 2014年 / 22卷

关键词：

Pneumomediastinum; Pneumonia; Pneumocystis jirovecii; HIV; PNEUMOCYSTIS-CARINII-PNEUMONIA; ACTIVE ANTIRETROVIRAL THERAPY; HIV-INFECTED PATIENTS; JIROVECII PNEUMONIA; CYSTIC LESIONS; ETIOLOGY; ERA; CT;

D O I：

10.1016/j.ijid.2013.12.009

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Objective: Pneumomediastinum is a rare complication of opportunistic infections in HIV-infected patients. However, the relationship between the causative pathogens and the prognosis is unclear. We report the case of a patient with AIDS presenting with community-acquired pneumonia complicated by pneumomediastinum. The cases of a further 10 HIV-infected patients with pneumomediastinum reported in the English language literature are reviewed. Methods: PubMed was searched for cases of HIV-infected patients with pneumomediastinum published in the English language literature. Results: Pneumocystis jirovecii is the most common pathogen causing pneumonia and concurrent pneumomediastinum in HIV-infected patients. Only one of the identified cases was caused by cytomegalovirus. Excluding the two cases with incomplete information, the overall mortality rate in the remaining nine cases was 55.5%. Conclusion: In HIV-infected patients, Pneumocystis jirovecii pneumonia can occasionally present as pneumomediastinum. In such cases, adequate appropriate antimicrobial therapy is needed due to the high mortality rate. (C) 2014 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. All rights reserved.

引用

页码：31 / 34

页数：4

共 21 条

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