Chronic Myelogenous Leukemia Presenting as a Secondary Malignancy After BCR-ABL1-negative B-lymphoblastic Leukemia/Lymphoma in a Pediatric Patient

被引：0

作者：

Popa, Gheorghe ^{[1
]}

Blag, Cristina ^{[1
]}

Olteanu, Horatiu ^{[2
]}

机构：

[1] Iuliu Hatieganu Univ Med & Pharm, Pediat Clin 2, Dept Pediat Oncol, Cluj Napoca, Romania

[2] Med Coll Wisconsin, Dept Pathol, 8701 Watertown Plank Rd, Milwaukee, WI 53226 USA

来源：

PEDIATRIC AND DEVELOPMENTAL PATHOLOGY | 2017年 / 20卷 / 01期

关键词：

chronic myelogenous leukemia; lymphoblastic leukemia/lymphoma; cytogenetics; flow cytometry; BCR-ABLI; CHRONIC MYELOID-LEUKEMIA; CHRONIC GRANULOCYTIC-LEUKEMIA; CHILDREN;

D O I：

10.1177/1093526616671047

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Chronic myelogenous leukemia, BCR-ABL1 positive (CML) is a rare myeloproliferative neoplasm in children and presents even less often as a secondary malignancy in the pediatric population. Below, we report a patient with Philadelphia-negative B-lymphoblastic leukemia/lymphoma, who developed CML several years after achieving complete remission, and summarize the existing literature on the clinical and pathologic features of CML as a secondary pediatric malignancy.

引用

页码：58 / 62

页数：5

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