Application of MBG as a coating material on mechanically stronger but less degradable ceramic scaffolds for enhanced osteogenesis

被引：6

作者：

Ye, Dandan ^{[1
,2
]}

Tang, Wei ^{[2
]}

Xu, Zhengjiang ^{[2
]}

Zhao, Xiaobing ^{[1
]}

Wang, Guocheng ^{[2
]}

机构：

[1] Changzhou Univ, Sch Mat Sci & Engn, Changzhou 213164, Peoples R China

[2] Chinese Acad Sci, Shenzhen Inst Adv Technol, Inst Biomed & Biotechnol, Shenzhen 518055, Peoples R China

来源：

MATERIALS LETTERS | 2018年 / 223卷

关键词：

Hardystonite scaffold; Mesoporous bioactive glass; Mechanical strength; Bioactive ions; Osteogenesis; Ceramic; BIOACTIVE GLASS; BONE; REGENERATION; BIOCERAMICS;

D O I：

10.1016/j.matlet.2018.03.202

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Improving the mechanical properties and maintaining the desired degradability of the bioceramic scaffold is always being a contradiction in the field of bone tissue engineering. To resolve this conflict, highly degradable mesoporous bioactive glass (MBG) was homogenously coated on the mechanically stronger hardystonite (Ca2ZnSi2O7, HT) scaffolds. The presence of MBG on the scaffold covers the shortage of the bioactive ions released from the underlying HT scaffold in the initial stage and provides a better platform for cellular adhesion. Results proved that the HT scaffold coated with MBG (HT/M) exhibited appealing biological properties, pointing out their potential application in bone tissue engineering. (C) 2018 Elsevier B.V. All rights reserved.

引用

页码：105 / 108

页数：4

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