1,2,3-Triazine Scaffold as a Potent Biologically Active Moiety: A Mini Review

被引：47

作者：

Kumar, Rajeev ^{[1
]}

Singh, Amar Deep ^{[1
]}

Singh, Jitendra ^{[1
]}

Singh, Hariram ^{[1
]}

Roy, R. K. ^{[1
]}

Chaudhary, Anurag ^{[2
]}

机构：

[1] Dr KN Modi Inst Pharmaceut Educ & Res, Ghaziabad 201201, UP, India

[2] Meerut Inst Engn & Technol, Dept Pharmaceut Technol, Meerut 250005, Uttar Pradesh, India

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2014年 / 14卷 / 01期

关键词：

Anticancer activity; antimicrobial activity; antiprotozoal; in vivo; 1,2,3-triazine; BENZOTRIAZINE BASED COMPOUNDS; NEMATOCIDAL ACTIVITY; CYTOTOXIC ACTIVITY; KINASE INHIBITOR; ANTITUMOR; DERIVATIVES; SERIES; 6-AZAURIDINE; ANALOGS; DESIGN;

D O I：

10.2174/1389557513666140103111017

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

1,2,3-Triazine is an interesting class of heterocyclic compounds. Various synthetic analogs of 1,2,3-triazine have been prepared and evaluated for many pharmacological activities in different models with desired findings. Some analogs have shown potent pharmacological activity and may be considered as lead molecule for the development of future drugs. This review is an attempt to organize the chemical and pharmacological aspects of 1,2,3-triazine analogs reported till date systematically since 1970.

引用

页码：72 / 83

页数：12

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