Highly enantiospecific oxyfunctionalization of nonactivated hydrocarbon sites by perfluoro-cis-2-n-butyl-3-n-propyloxaziridine

被引：17
作者：
Arnone, A
Folettto, S
Metrangolo, P
Pregnolato, M
Resnati, G
机构：
[1] Polytechn Milano, Dept Chem, I-20131 Milan, Italy
[2] Univ Pavia, Dept Pharmaceut Chem, I-27100 Pavia, Italy
来源：
ORGANIC LETTERS | 1999年 / 1卷 / 02期
关键词：
D O I：
10.1021/ol990594e
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] Nonactivated hydrocarbon sites of enantiopure compounds are oxyfunctionalized enantiospecifically by perfluoro-cis-2-n-butyl-3-n-propyloxaziridine under remarkably mild reaction conditions. The reaction occurs with retention of configuration at the oxidized stereogenic center, and the enantiospecificity is highly independent from both the carbon framework of the substrate and the presence of functional groups.
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收藏
页码：281 / 284
页数：4
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