Commentary: Using human genetics to guide the repurposing of medicines

被引:3
作者
Bovijn, Jonas [1 ,2 ]
Censin, Jenny C. [1 ,2 ]
Lindgren, Cecilia M. [1 ,2 ,3 ,4 ]
Holmes, Michael V. [1 ,3 ,5 ,6 ,7 ]
机构
[1] Univ Oxford, Big Data Inst, Li Ka Shing Ctr Hlth Informat & Discovery, Old Rd Campus,Old Rd, Oxford OX3 7FZ, England
[2] Univ Oxford, Wellcome Ctr Human Genet, Oxford, England
[3] Oxford Univ Hosp NHS Fdn Trust, Natl Inst Hlth Res Oxford Biomed Res Ctr, John Radcliffe Hosp, Oxford, England
[4] Broad Inst, Program Med & Populat Genet, Cambridge, MA USA
[5] Univ Oxford, Clin Trial Serv Unit, Nuffield Dept Populat Hlth, Oxford, England
[6] Univ Oxford, Epidemiol Studies Unit CTSU, Nuffield Dept Populat Hlth, Oxford, England
[7] Univ Oxford, Med Res Council Populat Hlth Res Unit MRC PHRU, Nuffield Dept Populat Hlth, Oxford, England
基金
美国国家卫生研究院; 英国医学研究理事会; 英国惠康基金;
关键词
MENDELIAN RANDOMIZATION; AMYLOID-BETA; DISEASE; RISK; TARGET; ACE;
D O I
10.1093/ije/dyaa015
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
引用
收藏
页码:1140 / 1146
页数:7
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