Spontaneous regression of metastatic cancer: learning from neuroblastoma

被引：35

作者：

Diede, Scott J. ^{[1
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, Div Clin Res, Seattle, WA 98109 USA

来源：

NATURE REVIEWS CANCER | 2014年 / 14卷 / 02期

关键词：

D O I：

10.1038/nrc3656

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Several interesting biological questions arise when thinking about the heterogeneous presentation of neuroblastoma, especially with regard to the molecular differences between very low- and high-risk disease. Why do some metastatic tumours spontaneously differentiate or regress entirely? Does the presence of disseminated disease always indicate metastases, or might some cases be better considered as multifocal disease?

引用

页码：71 / 72

页数：2

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