Antiarrhythmic Activity of Phytoadaptogens in Short-Term Ischemia-Reperfusion of the Heart and Postinfarction Cardiosclerosis

被引：25

作者：

Maslov, L. N. ^{[1
]}

Lishmanov, Yu. B. ^{[1
]}

Arbuzov, A. G. ^{[2
]}

Krylatov, A. V. ^{[1
]}

Budankova, E. V. ^{[1
]}

Konkovskaya, Yu. N. ^{[1
]}

Burkova, V. N. ^{[2
]}

Severova, E. A. ^{[3
]}

机构：

[1] Russian Acad Med Sci, Inst Cardiol, Tomsk Res Ctr, Siberian Div, Tomsk, Russia

[2] Biolit Firm, Tomsk, Russia

[3] Minist Hlth Kazakhstan, Inst Cardiol & Visceral Dis, Alma Ata, Kazakhstan

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2009年 / 147卷 / 03期

关键词：

adaptogens; ischemia; reperfusion; cardiosclerosis; arrhythmia;

D O I：

10.1007/s10517-009-0502-6

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

A course of treatment (16 mg/kg orally during 5 days) by Aralia mandshurica or Rhodiola rosea extracts reduced the incidence of ischemic and reperfusion ventricular arrhythmias during 10-min ischemia and 10-min reperfusion. Extracts of Eleutherococcus senticosus, Leuzea carthamoides, and Panax ginseng did not change the incidence of ischemic and reperfusion arrhythmias. Chronic treatment by aralia, rhodiola, and eleutherococcus elevated the ventricular fibrillation threshold in rats with postinfarction cardiosclerosis. Ginseng and leuzea did not change this parameter in rats with postinfarction cardiosclerosis.

引用

页码：331 / 334

页数：4

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