Synthesis of mono- and symmetrical di-N-hydroxy- and N-aminoguanidines

被引：13
作者：
Katritzky, Alan R. [1 ]
Khashab, Niveen M. [1 ]
Bobrov, Sergey [1 ]
Yoshioka, Megumi [1 ]
机构：
[1] Univ Florida, Dept Chem, Ctr Heterocycl Cpds, Gainesville, FL 32611 USA
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 71卷 / 18期
关键词：
D O I：
10.1021/jo060793t
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Novel mono- and symmetrical di-N-hydroxy- and N-aminoguanidines were readily prepared from the reaction of diverse hydroxylamines or hydrazines with reagent classes di(benzotriazol-1-yl) methanimine 6, (bis-benzotriazol-1-yl-methylene) amines 8a, b, benzotriazole-1-carboxamidines 10a-i, benzotriazole-1-carboximidamides 11a,b, and N'-hydroxy-1H-1,2,3-benzotriazole-1-carboximidamide 18. The preparation is described for a variety of N-hydroxy- and N-aminoguanidines with different substitution patterns in good yields.
引用
收藏
页码：6753 / 6758
页数：6
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