Methicillin-susceptible Staphylococcus aureus CC398: First description in prosthetic joint infection and genetic background comparison with nasal carriage isolates

被引：6
作者：
Aubin, Guillaume G. [1 ,2 ]
Lepelletier, Didier [1 ,2 ]
Reynaud, Alain [1 ,2 ]
Lavigne, Jean-Philippe [3 ,4 ]
Corvec, Stephane [1 ,2 ]
机构：
[1] Fac Med, EA3826, Nantes, France
[2] CHU Nantes, Serv Bacteriol Hyg Hosp, F-44093 Nantes 01, France
[3] Univ Montpellier I, INSERM, U1047, Nimes, France
[4] CHU Caremeau, Lab Bacteriol, Nimes, France
来源：
JOURNAL OF INFECTION AND CHEMOTHERAPY | 2014年 / 20卷 / 5-6期
关键词：
Livestock associated Staphylococcus aureus; CC398; Prosthetic-related infection; DNA microarray; LIVESTOCK; RESISTANCE; HUMANS; EMERGENCE; ST398; PIGS;
D O I：
10.1016/j.jiac.2014.03.007
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Few reports described infections with CC398 methicillin-susceptible Staphylococcus aureus (MSSA). We compared the genetic background of CC398 MSSA strains from nasal carriage and knee arthroplasty infection. DNA microarray analysis shows acquisition of particular adhesin, iron capture system and immune defense evasion mechanisms. These characteristics could explain pathogenesis in this type of infection. (C) 2014, Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：394 / 396
页数：3
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