Fat body, fat pad and adipose tissues in invertebrates and vertebrates: the nexus

被引：81

作者：

Azeez, Odunayo Ibraheem ^{[1
,2
]}

Meintjes, Roy ^{[1
]}

Chamunorwa, Joseph Panashe ^{[1
]}

机构：

[1] Univ Pretoria, Fac Vet Sci, Dept Anat & Physiol, ZA-0110 Pretoria, South Africa

[2] Univ Ibadan, Fac Vet Med, Dept Vet Physiol Biochem & Pharmacol, Ibadan, Nigeria

来源：

LIPIDS IN HEALTH AND DISEASE | 2014年 / 13卷

关键词：

Fat body; Adipose tissue; Metabolic syndrome; ADIPOKINETIC HORMONES; APOLIPOPROTEIN-B; GENE-EXPRESSION; PROTEIN-CONTENT; LIPID DROPLETS; PGRP-LC; INFLAMMATION; DROSOPHILA; OBESITY; INSECT;

D O I：

10.1186/1476-511X-13-71

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The fat body in invertebrates was shown to participate in energy storage and homeostasis, apart from its other roles in immune mediation and protein synthesis to mention a few. Thus, sharing similar characteristics with the liver and adipose tissues in vertebrates. However, vertebrate adipose tissue or fat has been incriminated in the pathophysiology of metabolic disorders due to its role in production of pro-inflammatory cytokines. This has not been reported in the insect fat body. The link between the fat body and adipose tissue was examined in this review with the aim of determining the principal factors responsible for resistance to inflammation in the insect fat body. This could be the missing link in the prevention of metabolic disorders in vertebrates, occasioned by obesity.

引用

页数：13

共 100 条

[1] Chronic activation of the epithelial immune system of the fruit fly's salivary glands has a negative effect on organismal growth and induces a peculiar set of target genes [J].

Abdelsadik, Ahmed ;

Roeder, Thomas .

BMC GENOMICS, 2010, 11

[2] Toll-like receptor signalling [J].

Akira, S ;

Takeda, K .

NATURE REVIEWS IMMUNOLOGY, 2004, 4 (07) :499-511

[3] A novel role for lipid droplets in the organismal antibacterial response [J].

Anand, Preetha ;

Cermelli, Silvia ;

Li, Zhihuan ;

Kassan, Adam ;

Bosch, Marta ;

Sigua, Robilyn ;

Huang, Lan ;

Ouellette, Andre J. ;

Pol, Albert ;

Welte, Michael A. ;

Gross, Steven P. .

ELIFE, 2012, 1

[4] DEVELOPMENTAL-CHANGES IN PROTEIN-CONTENT, VOLUMES AND AMINO-ACID POOLS IN THE LARVAL FAT-BODY AND HEMOLYMPH OF CALLIPHORA-ERYTHROCEPHALA [J].

ANDERSON, OD .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 1984, 77 (01) :161-165

[5] Insect Fat Body: Energy, Metabolism, and Regulation [J].

Arrese, Estela L. ;

Soulages, Jose L. .

ANNUAL REVIEW OF ENTOMOLOGY, 2010, 55 :207-225

[6] Apolipophorin II/I, apolipoprotein B, vitellogenin, and microsomal triglyceride transfer protein genes are derived from a common ancestor [J].

Babin, PJ ;

Bogerd, J ;

Kooiman, FP ;

Van Marrewijk, WJA ;

Van der Horst, DJ .

JOURNAL OF MOLECULAR EVOLUTION, 1999, 49 (01) :150-160

[7]

Bajpai S, 2007, J BIOSCIENCE, V34, P673

[8] Inflammation and cancer: back to Virchow? [J].

Balkwill, F ;

Mantovani, A .

LANCET, 2001, 357 (9255) :539-545

[9] Adipose tissue inflammation and cancer cachexia: Possible role of nuclear transcription factors [J].

Batista, M. L., Jr. ;

Peres, S. B. ;

McDonald, M. E. ;

Alcantara, P. S. M. ;

Olivan, M. ;

Otoch, J. P. ;

Farmer, S. R. ;

Seelaender, M. .

CYTOKINE, 2012, 57 (01) :9-16

[10] The regulation of trehalose metabolism in insects [J].

Becker, A ;

Schloder, P ;

Steele, JE ;

Wegener, G .

EXPERIENTIA, 1996, 52 (05) :433-439

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