Carbon-Based Quantum Dots for Electrochemical Detection of Monoamine Neurotransmitters-Review

被引:31
作者
Elugoke, Saheed E. [1 ,2 ]
Adekunle, Abolanle S. [1 ,2 ,3 ]
Fayemi, Omolola E. [1 ,2 ]
Mamba, Bhekie B. [4 ]
Sherif, El-Sayed M. [5 ,6 ]
Ebenso, Eno E. [1 ,7 ]
机构
[1] North West Univ, Fac Nat & Agr Sci, Mat Sci Innovat & Modelling MaSIM Res Focus Area, Mafikeng Campus, ZA-2735 Mmabatho, South Africa
[2] North West Univ, Fac Nat & Agr Sci, Sch Phys & Chem Sci, Dept Chem, Mafikeng Campus, ZA-2735 Mmabatho, South Africa
[3] Obafemi Awolowo Univ, Dept Chem, Ife 220005, Nigeria
[4] Univ South Africa, Coll Sci Engn & Technol, Nanotechnol & Water Sustainabil Res Unit, ZA-1709 Johannesburg, South Africa
[5] King Saud Univ, Ctr Excellence Res Engn Mat CEREM, POB 800, Riyadh 11421, Saudi Arabia
[6] Natl Res Ctr, Dept Phys Chem, Electrochem & Corros Lab, Cairo 12622, Egypt
[7] Univ South Africa, Coll Sci Engn & Technol, Dept Chem, ZA-1710 Roodepoort, South Africa
来源
BIOSENSORS-BASEL | 2020年 / 10卷 / 11期
关键词
carbon quantum dots; graphene quantum dots; neurotransmitters; electrochemical sensors; HIGHLY SENSITIVE DETECTION; SELF-ASSEMBLED MONOLAYERS; ELECTRODE-BASED SENSOR; VOLTAMMETRIC DETERMINATION; ASCORBIC-ACID; IONIC LIQUID; URIC-ACID; CATECHOLAMINE NEUROTRANSMITTERS; FUNCTIONALIZED GRAPHENE; OXIDE NANOPARTICLES;
D O I
10.3390/bios10110162
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Imbalance in the levels of monoamine neurotransmitters have manifested in severe health issues. Electrochemical sensors have been designed for their determination, with good sensitivity recorded. Carbon-based quantum dots have proven to be an important component of electrochemical sensors due to their high conductivity, low cytotoxicity and opto-electronic properties. The quest for more sensitive electrodes with cheaper materials led to the development of electrochemical sensors based on carbon-based quantum dots for the detection of neurotransmitters. The importance of monoamine neurotransmitters (NTs) and the good electrocatalytic activity of carbon and graphene quantum dots (CQDs and GQDs) make the review of the efforts made in the design of such sensors for monoamine NTs of huge necessity. The differences and the similarities between these two quantum dots are highlighted prior to a discussion of their application in electrochemical sensors over the last ten years. Compared to other monoamine NTs, dopamine (DA) was the most studied with GQDs and CQD-based electrochemical sensors.
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页数:41
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