Homologous recombination in human embryonic stem cells using CRISPR/Cas9 nickase and a long DNA donor template

被引：58

作者：

Rong, Zhili ^{[2
]}

Zhu, Shengyun ^{[1
]}

Xu, Yang ^{[2
]}

Fu, Xuemei ^{[1
,3
]}

机构：

[1] Shenzhen Childrens Hosp, Shenzhen 518026, Peoples R China

[2] Univ Calif San Diego, Div Biol Sci, La Jolla, CA 92093 USA

[3] Chongqing Med Univ, Chongqing 400016, Peoples R China

来源：

PROTEIN & CELL | 2014年 / 5卷 / 04期

关键词：

HUMAN ESCS; GENOME; CAS9; SPECIFICITY; NUCLEASES; GENERATION; SYSTEM; GENES; MICE;

D O I：

10.1007/s13238-014-0032-5

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

引用

页码：258 / 260

页数：3

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