High Prevalence of Abdominal Aortic Aneurysm in Patients with Three-vessel Coronary Artery Disease

被引:60
作者
Durieux, R. [1 ]
Van Damme, H. [1 ]
Labropoulos, N. [2 ]
Yazici, A. [1 ]
Legrand, V. [3 ]
Albert, A. [4 ]
Defraigne, J. -O. [1 ]
Sakalihasan, N. [1 ]
机构
[1] Univ Hosp Liege, Dept Cardiovasc & Thorac Surg, B-4000 Liege, Belgium
[2] SUNY Stony Brook, Dept Vasc Surg, Med Ctr, Stony Brook, NY 11794 USA
[3] Univ Hosp Liege, Dept Cardiol, B-4000 Liege, Belgium
[4] Univ Hosp Liege, Dept Med Informat & Biostat, B-4000 Liege, Belgium
关键词
Abdominal aortic aneurysm; Coronary artery disease; Screening; RANDOMIZED CONTROLLED-TRIAL; TRANSTHORACIC ECHOCARDIOGRAPHY; MORTALITY; AGE; ATHEROSCLEROSIS; POPULATION; AUSTRALIA;
D O I
10.1016/j.ejvs.2013.12.011
中图分类号
R61 [外科手术学];
学科分类号
摘要
Objectives: Currently, the prevalence of abdominal aortic aneurysm (AAA) in patients with coronary artery disease (CAD) and the correlation between CAD severity and AAA prevalence are not clearly known. We conducted a prospective study to determine the prevalence of AAA in patients undergoing coronary angiography and to determine the risk factors and a coronary profile associated with AM. Methods: Over an 18-month period, abdominal aortic ultrasound was performed on 1,000 patients undergoing coronary angiography for suspected or known CAD, or prior to valve surgery. Clinical characteristics and coronary profile were collected from the patients. Results: The overall number of previously repaired, already diagnosed, and new cases of AAA in the study population was 42, yielding a prevalence of 4.2%. Among the patients with newly detected AAAs, only two had an AAA diameter of >54 mm and were therefore treated surgically. In men aged >= 65 years, the prevalence reached 8.6%, while in men with three-vessel CAD it was 14.4%. Multivariate analysis showed that age >= 65 years (p = .003), male gender (p = .003), family history of AAA (p = .01), current smoking (p = .002), and three-vessel CAD (p < .001) were significantly associated with a higher prevalence of AAA. Conclusion: The prevalence of AAA was high in men aged >= 65 years and in those with three-vessel CAD regardless of age. While our findings do not prove the cost-effectiveness of screening for AAA in these high risk patients, they do support the usefulness of a quick ultrasound examination of the abdominal aorta during routine transthoracic echocardiography in such patients. (C) 2013 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:273 / 278
页数:6
相关论文
共 34 条
[1]  
Aboyans V, 2012, CIRCULATION, V126, pA13479
[2]   Screening abdominal aorta aneurysm during echocardiography: Literature review and proposal for a French nationwide study [J].
Aboyans, Victor ;
Kownator, Serge ;
Lafitte, Marianne ;
Brochet, Eric ;
Emmerich, Joseph ;
Tribouilloy, Christophe ;
Lafitte, Stephane ;
Ferrinig, Marc .
ARCHIVES OF CARDIOVASCULAR DISEASES, 2010, 103 (10) :552-558
[3]   Selective screening for abdominal aortic aneurysm among patients referred to the vascular laboratory [J].
Alund, M. ;
Mani, K. ;
Wanhainen, A. .
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, 2008, 35 (06) :669-674
[4]   Is the Incidence of Abdominal Aortic Aneurysm Declining in the 21st Century? Mortality and Hospital Admissions for England & Wales and Scotland [J].
Anjum, A. ;
Powell, J. T. .
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, 2012, 43 (02) :161-166
[5]   The Multicentre Aneurysm Screening Study (MASS) into the effect of abdominal aortic aneurysm screening on mortality in men: a randomised controlled trial [J].
Ashton, HA ;
Buxton, MJ ;
Day, NE ;
Kim, LG ;
Marteau, TM ;
Scott, RAP ;
Thomspon, SG ;
Walker, NM .
LANCET, 2002, 360 (9345) :1531-1539
[6]   A randomized controlled trial of endovascular aneurysm repair versus open surgery for abdominal aortic aneurysms in low- to moderate-risk patients [J].
Becquemin, Jean-Pierre ;
Pillet, Jean-Chistophe ;
Lescalie, Francois ;
Sapoval, Marc ;
Goueffic, Yann ;
Lermusiaux, Patrick ;
Steinmetz, Eric ;
Marzelle, Jean .
JOURNAL OF VASCULAR SURGERY, 2011, 53 (05) :1167-1173
[7]   Abdominal aortic aneurysm screening during transthoracic echocardiography in an unselected population [J].
Bekkers, SCAM ;
Habets, JHM ;
Cheriex, EC ;
Palmans, A ;
Pinto, Y ;
Hofstra, L ;
Crijns, HJGM .
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 2005, 18 (05) :389-393
[8]   Prevalence of abdominal aortic aneurysms in patients undergoing coronary artery bypass [J].
Bergersen, L ;
Kiernan, MS ;
McFarlane, G ;
Case, TD ;
Ricci, MA .
ANNALS OF VASCULAR SURGERY, 1998, 12 (02) :101-105
[9]   Screening for abdominal aortic aneurysm in coronary care unit patients with acute myocardial infarction using portable transthoracic echocardiography [J].
Cueff, Caroline ;
Keenan, Niall G. ;
Krapf, Laura ;
Steg, Philippe Gabriel ;
Cimadevilla, Claire ;
Ducrocq, Gregory ;
Michel, Jean-Baptiste ;
Vahanian, Alec ;
Messika-Zeitoun, David .
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, 2012, 13 (07) :574-578
[10]   TIMP-2 and PAI-1 mRNA levels are lower in aneurysmal as compared to athero-occlusive abdominal aortas [J].
Defawe, OD ;
Colige, A ;
Lambert, CA ;
Munaut, C ;
Delvenne, P ;
Lapière, CM ;
Limet, R ;
Nusgens, BV ;
Sakalihasan, N .
CARDIOVASCULAR RESEARCH, 2003, 60 (01) :205-213