Effect of dietary supplementation with flaxseed oil or vitamin E on sheep experimentally infected with Fasciola hepatica

被引：4

作者：

Martinez-Perez, J. M. ^{[1
]}

Robles-Perez, D. ^{[1
]}

Benavides, J. ^{[2
]}

Moran, L. ^{[2
]}

Andres, S. ^{[2
]}

Giraldez, F. J. ^{[2
]}

Rojo-Vazquez, F. A. ^{[1
,2
]}

Martinez-Valladares, M. ^{[2
]}

机构：

[1] Univ Leon, Fac Vet, Dept Sanidad Anim Parasitol & Enfermedades Parasi, E-24071 Leon, Spain

[2] Inst Ganaderia Montana CSIC ULE, Finca Marzanas, Grulleros 24346, Leon, Spain

来源：

RESEARCH IN VETERINARY SCIENCE | 2014年 / 97卷 / 01期

关键词：

Fasciola hepatica; Flaxseed oil; Vitamin E; Immune system; Sheep; IMMUNE-RESPONSE; GASTROINTESTINAL NEMATODES; OVINE FASCIOLIASIS; ANTIOXIDANT STATUS; CONDENSED TANNINS; CHICKEN MEAT; LIVER; STRESS; CATTLE; PERFORMANCE;

D O I：

10.1016/j.rvsc.2014.05.009

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The effects of two diets supplemented with flaxseed oil (FO) or vitamin E (VE) were studied in sheep infected with Fasciola hepatica. The control group (CO), not supplemented, had higher weight gain and faecal egg count (P<0.05) at the end of the study. At necropsy, the number (71.2 +/- 26.5) and size of flukes were lower in the FO group (P<0.01), probably due to the higher levels of white blood cells and lymphocytes (P<0.01). This group also had higher red blood cell and haematocrit values (P<0.01). The CO group had more severe hypoproteinaemia and hypoalbuminaemia, due to having the highest fluke burden (123.0 +/- 35.2), and also the highest IgG1 titre (P<0.01). The diet did not affect production or gene expression levels of IFN-gamma and IL-4. On the other hand, the supplementation with VE led to a reduction in adult fluke burden (97.7 +/- 39.9) and lower lipid oxidation in the liver (P<0.001). (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：71 / 79

页数：9

共 61 条

[1] MM3-ELISA evaluation of coproantigen release and serum antibody production in sheep experimentally infected with Fasciola hepatica and F-gigantica [J].

Adela Valero, M. ;

Ubeira, Florencio M. ;

Khoubbane, Messaoud ;

Artigas, Patricio ;

Muino, Laura ;

Mezo, Mercedes ;

Perez-Crespo, Ignacio ;

Victoria Periago, M. ;

Mas-Coma, Santiago .

VETERINARY PARASITOLOGY, 2009, 159 (01) :77-81

[2]

[Anonymous], 2000, MERCK VET MANUAL

[3] Direct anthelmintic effects of condensed tannins towards different gastrointestinal nematodes of sheep: in vitro and in vivo studies [J].

Athanasiadou, S ;

Kyriazakis, I ;

Jackson, F ;

Coop, RL .

VETERINARY PARASITOLOGY, 2001, 99 (03) :205-219

[4] Testing for direct anthelmintic effects of bioactive forages against Trichostrongylus colubriformis in grazing sheep [J].

Athanasiadou, S ;

Tzamaloukas, O ;

Kyriazakis, I ;

Jackson, F ;

Coop, RL .

VETERINARY PARASITOLOGY, 2005, 127 (3-4) :233-243

[5]

Benjamin MM, 1984, MANUAL PARASITOLOGIA, P135

[6] The liver antioxidant status of fattening lambs is improved by naringin dietary supplementation at 0.15% rates but not meat quality [J].

Bodas, R. ;

Prieto, N. ;

Jordan, M. J. ;

Lopez-Campos, O. ;

Giraldez, F. J. ;

Moran, L. ;

Andres, S. .

ANIMAL, 2012, 6 (05) :863-870

[7] Humoral immune response in calves to single-dose, trickle and challenge infections with Fasciola hepatica [J].

Bossaert, K ;

Farnir, F ;

Leclipteux, T ;

Protz, M ;

Lonneux, JF ;

Losson, B .

VETERINARY PARASITOLOGY, 2000, 87 (2-3) :103-123

[8]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[9] Influence of stress and nutrition on cattle immunity [J].

Carroll, Jeffery A. ;

Forsberg, Neil E. .

VETERINARY CLINICS OF NORTH AMERICA-FOOD ANIMAL PRACTICE, 2007, 23 (01) :105-+

[10] Immune responses of chronically infected adult cattle to Fasciola hepatica [J].

Clery, D ;

Torgerson, P ;

Mulcahy, G .

VETERINARY PARASITOLOGY, 1996, 62 (1-2) :71-82

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