Acute Delayed Infection: Increased Risk in Failed Metal on Metal Total Hip Arthroplasty

被引：30

作者：

Prieto, Hernan A. ^{[1
]}

Berbari, Elie F. ^{[1
]}

Sierra, Rafael J. ^{[1
]}

机构：

[1] Mayo Clin, Rochester, MN 55905 USA

来源：

JOURNAL OF ARTHROPLASTY | 2014年 / 29卷 / 09期

关键词：

Metal-on-metal; complications; revision arthroplasty; total hip arthroplasty; infection; PROSTHETIC JOINT INFECTION; ON-METAL; SYNOVIAL-FLUID; FAILURE; HYPERSENSITIVITY; SYSTEM; COBALT; IONS;

D O I：

10.1016/j.arth.2014.04.008

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Adverse local tissue reactions occurring in metal-on-metal total hip arthroplasty (MoM THA) could potentially lead to secondary failure modes such as dislocation or infection. The authors report a series of 124 patients treated with MoM hip arthroplasty between 2006 and 2010 with a minimum follow-up of 3 years. Eight hips presented with acute delayed or late periprosthetic joint infection (PJI) (defined as an infection occurring after 3 months in an otherwise well functioning implant). The rate of infection observed was higher than expected, almost 4 times higher (5.6%) compared to previous historical cohorts from our institution (1.3%). This high risk of infection in patients with DePuy ASR implants requires further study but we theorize that the increased prevalence of infection could be due to a combination of particulate debris, molecular (rather than particulate) effects of Co and Cr ions on soft tissues, and/or products of corrosion that may change the local environment predisposing to infection. (C) 2014 Elsevier Inc. All rights reserved.

引用

页码：1808 / 1812

页数：5

共 34 条

[1]

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