Detection of Toxoplasma gondii in Cord Blood Samples from Neonates in Tehran, Iran

被引：0

作者：

Nahvi, Moloud ^{[1
]}

Shojaee, Saeedeh ^{[1
]}

Keshavarz, Hossein ^{[1
]}

Salimi, Mahboobeh ^{[1
]}

Mohebali, Mehdi ^{[1
]}

机构：

[1] Univ Tehran Med Sci, Sch Publ Hlth, Dept Med Parasitol & Mycol, Tehran, Iran

来源：

IRANIAN JOURNAL OF PUBLIC HEALTH | 2019年 / 48卷 / 05期

关键词：

Toxoplasma gondii; ELISA; Cord blood; IgG antibody; IgM antibody; PREGNANT-WOMEN; AVIDITY; SEROPREVALENCE; PREVALENCE; ANTIBODIES; DIAGNOSIS; PROVINCE; ELISA;

D O I：

暂无

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background: Toxoplasmosis is an infectious disease caused by the coccidian protozoan parasite Toxoplasma gondii. The infection is life-threatening in congenital form because of transmission of the parasite from mother to fetus. In order to investigate the prevalence of congenital toxoplasmosis, the present study was performed for detection of IgG and IgM antibodies in cord blood samples of newborns by ELISA method in Tehran, Iran. Methods: This cross-sectional survey was carried out on 1000 cord blood samples collected from Shahid Mostafa Khomeini Hospital in Tehran, Iran in 2015. Sera were separated and evaluated for the presence of IgG and IgM antibodies against T. gondii by ELISA method. At the same time, whole cord blood samples were stored at 20 degrees C for complementary PCR test. Results: From 1000 cord blood serum samples 198 cases (19.8%) were positive for anti T. gondii IgG antibody. IgG positive samples were examined for IgM antibody, among them 1 sample had borderline levels of IgM antibody. PCR was performed for this sample but no positive result was seen. Conclusion: Although congenital toxoplasmosis is of importance, no acute form of infection was seen in pregnant women in this study.

引用

页码：912 / 916

页数：5

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