The neurological complications of chikungunya virus: A systematic review

被引：165

作者：

Mehta, Ravi ^{[1
,8
]}

Gerardin, Patrick ^{[2
,3
]}

Antunes de Brito, Carlos Alexandre ^{[4
]}

Soares, Cristiane Nascimento ^{[5
]}

Brito Ferreira, Maria Lucia ^{[6
]}

Solomon, Tom ^{[1
,7
,8
]}

机构：

[1] Univ Liverpool, Natl Inst Hlth Res, Hlth Protect Res Unit Emerging & Zoonot Infect, Liverpool, Merseyside, England

[2] CHU Reunion, INSERM, CIC1410, St Pierre, Reunion, France

[3] Univ Reunion, CHU, CYROI, UM PIMIT CNRS 9192 134,INSERM,U1187,IRD 249, St Pierre, Reunion, France

[4] Univ Fed Pernambuco, Dept Infect Dis, Recife, PE, Brazil

[5] Hosp Fed Servidores Estado, Dept Neurol, Rio De Janeiro, Brazil

[6] Hosp Restauracao, Dept Neurol, Ave Agamenon Magalhaes, Recife, PE, Brazil

[7] Walton Ctr NHS Fdn Trust, Dept Neurol, Liverpool, Merseyside, England

[8] Univ Liverpool, Inst Infect & Global Hlth, Liverpool L69 7BE, Merseyside, England

来源：

REVIEWS IN MEDICAL VIROLOGY | 2018年 / 28卷 / 03期

基金：

英国医学研究理事会;

关键词：

acute disseminated encephalomyelitis; chikungunya; complications; congenital infections; encephalitis; Guillain-Barre syndrome; myelitis; neonatal infection; neurological; optic neuritis; retinitis; uveitis; GUILLAIN-BARRE-SYNDROME; ZIKA VIRUS; NEONATAL CHIKUNGUNYA; HEMORRHAGIC-FEVER; CASE DEFINITIONS; REUNION ISLAND; SINGLE-CENTER; INFECTION; MANIFESTATIONS; DENGUE;

D O I：

10.1002/rmv.1978

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We performed a systematic review on the neurological complications of chikungunya virus. Such complications are being reported increasingly, owing primarily to the scale of recent epidemics but also to a growing understanding of the virus' neurovirulence. We performed a thorough literature search using PubMed and Scopus databases, summating the data on all published reports of neurological disease associated with chikungunya virus. We appraised the data for each major condition in adults, children, and neonates, as well as evaluating the latest evidence on disease pathogenesis and management strategies. The review provides a comprehensive summary for clinicians, public health officials, and researchers tackling the challenges associated with this important emerging pathogen.

引用

页数：24

共 143 条

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