Comparison of toxicity and outcome in advanced stage non-small cell lung cancer patients treated with intensity-modulated (chemo-) radiotherapy using IMRT or VMAT

被引:37
作者
Wijsman, Robin [1 ]
Dankers, Frank [1 ]
Troost, Esther G. C. [2 ,3 ,4 ,5 ,6 ]
Hoffmann, Aswin L. [2 ,3 ]
van der Heijden, Erik H. F. M. [7 ]
de Geus-Oei, Lioe-Fee [8 ,9 ,10 ]
Bussink, Johan [1 ]
机构
[1] Radboud Univ Nijmegen, Med Ctr, Dept Radiat Oncol, Nijmegen, Netherlands
[2] Helmholtz Zentrum Dresden Rossendorf, Inst Radiooncol, Dresden, Germany
[3] Tech Univ Dresden, Dept Radiat Oncol, Univ Hosp Carl Gustav Carus, Dresden, Germany
[4] Natl Ctr Radiat Res Oncol, OncoRay, Dresden, Germany
[5] German Canc Consortium DKTK, Heidelberg, Germany
[6] Partnersite Dresden, Natl Ctr Tumor Dis, Dresden, Germany
[7] Radboud Univ Nijmegen, Med Ctr, Dept Pulm Dis, Nijmegen, Netherlands
[8] Leiden Univ, Med Ctr, Dept Radiol, Leiden, Netherlands
[9] Univ Twente, Biomed Photon Imaging Grp, MIRA Inst, Enschede, Netherlands
[10] Radboud Univ Nijmegen, Med Ctr, Dept Radiol & Nucl Med, Nijmegen, Netherlands
关键词
Non-small cell lung cancer; Intensity-modulated radiation therapy; Volumetric-modulated radiation therapy; Toxicity; CONCURRENT CHEMOTHERAPY; RADIATION PNEUMONITIS; ESOPHAGUS TOXICITY; ARC THERAPY; PREDICTION; DAMAGE; RISK;
D O I
10.1016/j.radonc.2016.11.015
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Retrospective evaluation of 188 advanced stage non-small cell lung cancer patients treated with IMRT or VMAT revealed a limited increase of moderate to severe acute esophageal toxicity after VMAT. Acute pulmonary toxicity and severe late toxicity were low. Overall survival did not differ between the IMRT and VMAT groups. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:295 / 299
页数:5
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