Occupational Determinants of Cumulative Lead Exposure Analysis of Bone Lead Among Men in the VA Normative Aging Study

被引：11
作者：
Ji, John S. [1 ]
Schwartz, Joel [1 ,2 ]
Sparrow, David [3 ,4 ]
Hu, Howard [5 ]
Weisskopf, Marc G. [1 ,2 ]
机构：
[1] Harvard Univ, Sch Publ Hlth, Dept Environm Hlth, Boston, MA 02215 USA
[2] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02215 USA
[3] VA Boston Healthcare Syst, Boston, MA USA
[4] Boston Univ, Sch Publ Hlth & Med, Boston, MA 02215 USA
[5] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON M5S 1A1, Canada
来源：
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE | 2014年 / 56卷 / 04期
关键词：
BLOOD LEAD; ELDERLY-MEN; UNITED-STATES; CARDIOVASCULAR-DISEASE; BRAIN CANCER; HEALTH; POPULATION; WORKERS; HYPERTENSION; COHORT;
D O I：
10.1097/JOM.0000000000000127
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Objectives: To examine the relation between occupation and cumulative lead exposureassessed by measuring bone leadin a community-dwelling population. Method: We measured bone lead concentration with K-shell X-Ray Fluorescence in 1320 men in the Normative Aging Study. We categorized job titles into 14 broad US Census Bureau categories. We used ordinary least squares regression to estimate bone lead by job categories adjusted for other predictors. Results: Service workers, construction, and extractive craft workers and installation, maintenance, and repair craft workers had the highest bone lead concentrations. Including occupations significantly improved the overall model (P < 0.001) and reduced by 15% to 81% the association between bone lead and education categories. Conclusion: Occupation significantly predicts cumulative lead exposure in a community-dwelling population and accounts for a large proportion of the association between education and bone lead.
引用
收藏
页码：435 / 440
页数：6
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