Distribution of human papillomavirus genotypes (2014-2016) in women with genital warts at a sexually transmitted disease clinic in Beijing, China

被引:5
作者
Ma, Liang [1 ]
Lu, Shuang [1 ]
Jiang, Yongwei [1 ]
Li, Min [2 ]
Cong, Xiao [1 ]
Cao, Yongtong [1 ]
机构
[1] China Japan Friendship Hosp, Dept Clin Lab, Beijing 100029, Peoples R China
[2] China Japan Friendship Hosp, Dept Obstet & Gynecol, Beijing 100029, Peoples R China
关键词
Beijing; China; distribution; genital warts; human papillomavirus; HPV; prevalence; sexually transmitted disease; subtype; vaccines; women; ASIA-PACIFIC REGION; NATURAL-HISTORY; CERVICAL-CANCER; HPV; INFECTION; VACCINE; MULTICENTER; PREVALENCE; LESIONS; ISSUES;
D O I
10.2217/fvl-2017-0097
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Aim: The aim of this study was to analyze the distribution of human papillomavirus (HPV) genotypes among women with genital warts in the Beijing region of China. Methods: A total of 350 women diagnosed with genital warts between 2014 and 2016 were analyzed by real-time polymerase chain reaction (PCR) to test for high-risk and low-risk HPV subtypes. Results: The results show that 52.6% (184/350) of cases were positive for HPV6+ 11. The three most common high-risk HPVs detected were HPV52, HPV16 and HPV58, detected in 12.0% (42/350), 10.6% (37/350) and 10.0% (35/350) of all cases, respectively. Conclusion: These results indicate that vaccines targeting HPV subtypes 6, 11, 16, 52 and 58 would have the greatest impact among sexually active women living in Beijing.
引用
收藏
页码:111 / 117
页数:7
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