A hepatitis B virus flare that led to hepatic decompensation and liver transplantation in a pregnant woman with chronic hepatitis B: a rare case report and literature review

被引:0
作者
Yin, Chih-Hsiang [1 ]
Chang, Chia-Ching [1 ]
Lee, Yi-Liang [1 ]
Wu, Shou-En [1 ]
Lin, Yi-Hsin [1 ]
Kato, Paul Ivan [2 ]
Huang, Chuang-Yen [1 ]
机构
[1] Triserv Gen Hosp, Natl Def Med Ctr, Dept Obstet & Gynecol, Taipei 114, Taiwan
[2] Hoima Reg Referral Hosp, Dept Obstet & Gynecol, Hoima 7272, Uganda
关键词
Case report; Hepatitis B; Liver transplantation; Pregnancy; ANTIVIRAL THERAPY; FAILURE; RECIPIENTS; MANAGEMENT; INFECTION;
D O I
10.31083/j.ceog4907161
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Background: Acute viral hepatitis is the most common cause of jaundice during pregnancy. Distinct immunological changes during pregnancy and the postpartum period are possible crucial factors associated with flares of chronic hepatitis B. Case: We present the case of a healthy pregnant hepatitis B virus (HBV) carrier at 38 weeks of gestation. She underwent an emergent cesarean section due to acute hepatitis B flare, and ultimately underwent liver transplantation due to a decompensating liver based on an estimated Model for End-Stage Liver Disease score. Conclusions: For pregnant HBsAg positive women, close monitoring with serum HBV-DNA and spartate transaminase (AST)/alanine transaminase (ALT) levels every 3 months is highly recommended. According to the latest guidelines, prenatal antiviral therapy, postpartum HBV vaccination, and hepatitis B immunoglobulin should be administered to prevent mother-to-child transmission.
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页数:3
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共 12 条
  • [1] Management of chronic hepatitis B during pregnancy
    Aslam, Aysha
    Campoverde Reyes, Karen Joanie
    Malladi, Vijayram Reddy
    Ishtiaq, Rizwan
    Lau, Daryl T. Y.
    [J]. GASTROENTEROLOGY REPORT, 2018, 6 (04): : 257 - 262
  • [2] Hepatitis B Management in the Pregnant Patient: An Update
    Ayoub, Walid S.
    Cohen, Erica
    [J]. JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY, 2016, 4 (03) : 241 - 247
  • [3] Hepatitis B in pregnancy
    Borgia, Guglielmo
    Carleo, Maria Aurora
    Gaeta, Giovanni Battista
    Gentile, Ivan
    [J]. WORLD JOURNAL OF GASTROENTEROLOGY, 2012, 18 (34) : 4677 - 4683
  • [4] Antiviral therapy in chronic hepatitis B viral infection during pregnancy: A systematic review and meta-analysis
    Brown, Robert S., Jr.
    McMahon, Brian J.
    Lok, Anna S. F.
    Wong, John B.
    Ahmed, Ahmed T.
    Mouchli, Mohamed A.
    Wang, Zhen
    Prokop, Larry J.
    Murad, Mohammad Hassan
    Mohammed, Khaled
    [J]. HEPATOLOGY, 2016, 63 (01) : 319 - 333
  • [5] OUTCOME OF PERINATAL HEPATITIS-B VIRUS EXPOSURE IS DEPENDENT ON MATERNAL VIRUS LOAD
    BURK, RD
    HWANG, LY
    HO, GYF
    SHAFRITZ, DA
    BEASLEY, RP
    [J]. JOURNAL OF INFECTIOUS DISEASES, 1994, 170 (06) : 1418 - 1423
  • [6] Serum Alanine Aminotransferase and Hepatitis B DNA Flares in Pregnant and Postpartum Women with Chronic Hepatitis B
    Chang, Christine Y.
    Aziz, Natali
    Poongkunran, Mugilan
    Javaid, Asad
    Trinh, Huy N.
    Lau, Daryl
    Nguyen, Mindie H.
    [J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 2016, 111 (10) : 1410 - 1415
  • [7] Acute liver failure related to hepatitis B virus
    Lee, Han Chu
    [J]. HEPATOLOGY RESEARCH, 2008, 38 : S9 - S13
  • [8] Clinical course of hepatitis B virus infection during pregnancy
    Nguyen, G.
    Garcia, R. T.
    Nguyen, N.
    Trinh, H.
    Keeffe, E. B.
    Nguyen, M. H.
    [J]. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2009, 29 (07) : 755 - 764
  • [9] Acute liver failure in pregnancy: Challenges and management
    Pandey, Chandra Kant
    Karna, Sunaina Tejpal
    Pandey, Vijay Kant
    Tandon, Manish
    [J]. INDIAN JOURNAL OF ANAESTHESIA, 2015, 59 (03) : 144 - 149
  • [10] Pregnancy in liver transplant recipients: A single center outcomes
    Turkyilmaz, Gurcan
    Yasa, Cenk
    Dural, Ozlem
    Erturk, Emircan
    Kalelioglu, Ibrahim
    Has, Recep
    Yuksel, Atil
    [J]. JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, 2018, 44 (10) : 1882 - 1886