Chromosome-Based blaOXA-48-Like Variants in Shewanella Species Isolates from Food-Producing Animals, Fish, and the Aquatic Environment

被引:33
作者
Ceccarelli, Daniela [1 ]
van Essen-Zandbergen, Alieda [1 ]
Veldman, Kees T. [1 ]
Tafro, Nedzib [2 ]
Haenen, Olga [1 ]
Mevius, Dik J. [1 ,3 ]
机构
[1] Wageningen Biovet Res, Lelystad, Netherlands
[2] Dutch Food & Consumer Protect Author, Utrecht, Netherlands
[3] Univ Utrecht, Fac Vet Med, Utrecht, Netherlands
关键词
carbapenemase; OXA-48; antibiotic resistance; freshwater; fish; livestock; Shewanella; carbapenems; SALMONELLA-ENTERICA; ESCHERICHIA-COLI; RESISTANCE; CARBAPENEMASES; OXACILLINASE; PREVALENCE; EMERGENCE; CARRIAGE; BACTERIA; GENE;
D O I
10.1128/AAC.01013-16
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Carbapenems are considered last-resort antibiotics in health care. Increasing reports of carbapenemase-producing bacteria in food-producing animals and in the environment indicate the importance of this phenomenon in public health. Surveillance for carbapenemase genes and carbapenemase-producing bacteria in Dutch food-producing animals, environmental freshwater, and imported ornamental fish revealed several chromosome-based blaOXA-48-like variants in Shewanella spp., including two new alleles, blaOXA-514 and blaOXA-515. Carbapenemase genes were not associated with mobile genetic elements or Enterobacteriaceae.
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