In vivo optical bioimaging by using Nd-doped LaF3 luminescent nanorods in the second near-infrared window

被引：17

作者：

Cheng, Shouyan ^{[1
]}

Liu, Liu ^{[1
]}

Yang, Qiuhua ^{[1
]}

Li, Youbin ^{[1
]}

Zeng, Songjun ^{[1
]}

机构：

[1] Hunan Normal Univ, Synerget Innovat Ctr Quantum Effects & Applicat, Sch Phys & Elect,Minist Educ, Key Lab Low Dimens Quantum Struct & Quantum Contr, Changsha 410081, Hunan, Peoples R China

来源：

JOURNAL OF RARE EARTHS | 2019年 / 37卷 / 09期

基金：

中国国家自然科学基金;

关键词：

NIR-II imaging; Real-time tracking; Downshifting luminescence; Rare earths; UP-CONVERSION LUMINESCENCE; AG2S QUANTUM DOTS; CARBON NANOTUBES; DOWNCONVERSION PHOTOLUMINESCENCE; FLUORESCENCE; NANOPARTICLES; NANOCRYSTALS; NANOPROBES; EMISSION; BRIGHT;

D O I：

10.1016/j.jre.2018.11.014

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Fluorescent imaging in the second near-infrared (NIR-II, 1000-1700 nm) region has attracted enormous research interest due to its advantages of unprecedentedly improved imaging sensitivity and spatial resolution. Herein, high quality NIR-II emissive LaF3:Nd3+ nanorods (NRs) with hexagonal phase structure and controlled size were synthesized by a hydrothermal method. And the Nd3+ doping induced NIR-II luminescent intensity evolution was studied. In vivo NIR-II bioimaging and real-time tracking reveal that these LaF3:Nd3+ NRs are mainly accumulated in liver and spleen. Moreover, in vivo toxicity assessment demonstrates that LaF3:Nd3+ NRs feature low biotoxicity and good biocompatibility in living animals. Therefore, the NIR-II emitting hexagonal phase LaF3 NRs with controlled size are promising probes for optical bioimaging. (C) 2019 Chinese Society of Rare Earths. Published by Elsevier B.V. All rights reserved.

引用

页码：931 / 936

页数：6

共 56 条

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