Synthesis and bio-functionalization of multifunctional magnetic Fe3O4@Y2O3:Eu nanocomposites

被引:114
作者
Ma, Zhi Ya [1 ]
Dosev, Dosi [1 ]
Nichkova, Mikaela [2 ]
Gee, Shirley J. [2 ]
Hammock, Bruce D. [2 ]
Kennedy, Ian M. [1 ]
机构
[1] Univ Calif Davis, Dept Mech & Aeronaut Engn, Davis, CA 95616 USA
[2] Univ Calif Davis, Dept Entomol, Davis, CA 95616 USA
关键词
LN(3+)-DOPED LAF3 NANOPARTICLES; ONE-POT SYNTHESIS; FLUORESCENT NANOCOMPOSITES; SILICA NANOPARTICLES; OXIDE NANOPARTICLES; NANOCRYSTALS; LABELS; NANOSTRUCTURES; IMMUNOASSAY; PARTICLES;
D O I
10.1039/b901427f
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
A facile homogenous precipitation method has been developed for the synthesis of multifunctional, magnetic, luminescent nanocomposites with Fe3O4 nanoparticles as the core and europium-doped yttrium oxide (Y2O3:Eu) as the shell. The nanocomposites showed both super-paramagnetic behavior and unique europium fluorescence properties with high emission intensity. Their surface has been modified with a bifunctional ligand, p-aminobenzoic acid (PABA), and further biofunctionalized with biotin; the nanocomposites showed specific targeting for avidin-coupled polystyrene beads.
引用
收藏
页码:4695 / 4700
页数:6
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