Atypical Subacute Recurrence of Catastrophic Antiphospholipid Syndrome in a Japanese Female Patient

被引：3

作者：

Horikoshi, Masanobu

Inokuma, Shigeko

Matsubara, Erika

Honda, Yasunori

Okada, Rika

Kobuna, Mika

Miura, Yoko

Kobayashi, Shoko

Kawai, Shigeo

Kumasaka, Toshio

机构：

[1] Department of Allergy and Rheumatic Diseases, Japanese Red Cross Medical Center

[2] Department of Pathology, Japanese Red Cross Medical Center

来源：

INTERNAL MEDICINE | 2015年 / 54卷 / 22期

关键词：

catastrophic antiphospholipid syndrome; microangiopathic hemolytic anemia; relapse; rituximab; CLASSIFICATION; CRITERIA;

D O I：

10.2169/internalmedicine.54.5150

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Catastrophic antiphospholipid syndrome (CAPS) survivors rarely relapse. We herein report a case of a second CAPS episode with an unusual subacute course and no microangiopathic hemolytic anemia (MAHA), a common CAPS symptom. During the first episode, the 69-year-old woman responded well to high-dose glucocorticoids and plasma exchange. On relapse, these treatments plus rituximab were ineffective and she died of multi-organ failure and bacterial cholangitis. The absence of MAHA and a subacute course do not exclude a CAPS recurrence.

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收藏

页码：2923 / 2927

页数：5

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