Nortriterpenoids from the stems and leaves of Schisandra viridis

被引：15

作者：

Liu, Ye ^{[1
]}

Tian, Tian ^{[1
]}

Yu, Heng-Yi ^{[2
]}

Zhou, Ming ^{[1
]}

Ruan, Han-Li ^{[1
]}

机构：

[1] Huazhong Univ Sci & Technol, Hubei Key Lab Nat Med Chem & Resource Evaluat, Sch Pharm, Tongji Med Coll, Hangkonglu 13, Wuhan 430030, Peoples R China

[2] Huazhong Univ Sci & Technol, Tongji Hosp, Dept Pharm, Wuhan 430030, Peoples R China

来源：

FITOTERAPIA | 2017年 / 118卷

关键词：

Schisandra viridis; Schisandraceae; Nortriterpenoids; Cytotoxicity; HIGHLY OXYGENATED NORTRITERPENOIDS; CHINENSIS; TRITERPENOIDS; FRUITS; FAMILY;

D O I：

10.1016/j.fitote.2017.02.006

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

An extensive phytochemical study on the stems and leaves of Schisandra viridis A.C. Smith led to the isolation of two novel highly oxygenated schinortriterpenoids, pre-schisanartanin P (1) and wuweizidilactone Q(2), together with four known ones (3-6). Their structures with absolute configurations were established on the basis of comprehensive spectroscopic methods, including HRESIMS, ID and 2D NMR analyses and ECD experiments. All isolates were evaluated for their in vitro cytotoxicities against HepG2, MCF-7 and HT-29 cancer cell lines, none of them showed significant activities. (C) 2017 Elsevier B.V. All rights reserved.

引用

页码：38 / 41

页数：4

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