Chiral histone deacetylase inhibitors: Synthesis and biological evaluation

被引:0
|
作者
Onate, Alma [1 ]
Tucker, Janelle [1 ]
Hogle, Emily [1 ]
Do, Thuy [1 ]
Thowfeik, Fathima [2 ]
Merino, Edward [2 ]
Ma, Lili [1 ]
机构
[1] Northern Kentucky Univ, Chem, Hamilton, OH USA
[2] Univ Cincinnati, Chem, Cincinnati, OH USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
1144
引用
收藏
页数:1
相关论文
共 50 条
  • [41] Synthesis and biological evaluation of novel N-benzyltriazolyl-hydroxamate derivatives as selective histone deacetylase 6 inhibitors
    Kong, Sun Ju
    Nam, Gibeom
    Boggu, Pulla Reddy
    Park, Gi Min
    Kang, Ji Eun
    Park, Hyun-Ju
    Jung, Young Hoon
    BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 79
  • [42] Synthesis and evalution of new histone deacetylase inhibitors
    KrennHrubec, Keris
    Ulrich, Scott
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 233 : 848 - 848
  • [43] Synthesis of silane diol histone deacetylase inhibitors
    Salvaggio, Michael
    Ulrich, Scott M.
    Haaf, Michael
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 233 : 850 - 850
  • [44] Synthetic Routes and Biological Evaluation of Largazole and Its Analogues as Potent Histone Deacetylase Inhibitors
    Li, Shang
    Yao, Hequan
    Xu, Jinyi
    Jiang, Sheng
    MOLECULES, 2011, 16 (06): : 4681 - 4694
  • [45] Design, synthesis and biological activity of oxyevodiamine-based histone deacetylase 6 inhibitors
    Li, Si-Yuan
    Guo, Jiang-shan
    Yang, Ya-Jun
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2024, 26 (11) : 1328 - 1338
  • [46] Design, Synthesis, and Biological Activity of Boronic Acid-Based Histone Deacetylase Inhibitors
    Suzuki, Nobuaki
    Suzuki, Takayoshi
    Ota, Yosuke
    Nakano, Tatsuya
    Kurihara, Masaaki
    Okuda, Haruhiro
    Yamori, Takao
    Tsumoto, Hiroki
    Nakagawa, Hidehiko
    Miyata, Naoki
    JOURNAL OF MEDICINAL CHEMISTRY, 2009, 52 (09) : 2909 - 2922
  • [47] Design, synthesis and in vitro evaluation of amidoximes as histone deacetylase inhibitors for cancer therapy
    Jiao, Peifu
    Jin, Peng
    Li, Chencan
    Cui, Lechao
    Dong, Lihua
    Pan, Bin
    Song, Wentong
    Ma, Liang
    Dong, Jinlong
    Song, Lei
    Jin, Xinjie
    Li, Faming
    Wan, Maosheng
    Lv, Zhitao
    Geng, Qiaohong
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 26 (19) : 4679 - 4683
  • [48] Synthesis and Pharmacological Evaluation of Selective Histone Deacetylase 6 Inhibitors in Melanoma Models
    Tavares, Mauricio T.
    Shen, Sida
    Knox, Tessa
    Hadley, Melissa
    Kutil, Zsofia
    Barinka, Cyril
    Villagra, Alejandro
    Kozikowski, Alan P.
    ACS MEDICINAL CHEMISTRY LETTERS, 2017, 8 (10): : 1031 - 1036
  • [49] Synthesis of novel isoform selective histone deacetylase inhibitors containing chiral heterocyclic capping groups
    Matthews, Chris
    Marson, Charles
    Atkinson, Stephen
    Soden, Peter
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 248
  • [50] Synthesis and Biological Evaluation of N-Hydroxyphenylacrylamides and N-Hydroxypyridin-2-ylacrylamides as Novel Histone Deacetylase Inhibitors
    Thaler, Florian
    Colombo, Andrea
    Mai, Antonello
    Amici, Raffaella
    Bigogno, Chiara
    Boggio, Roberto
    Cappa, Anna
    Carrara, Simone
    Cataudella, Tiziana
    Fusar, Fulvia
    Gianti, Eleonora
    di Ventimiglia, Samuele Joppolo
    Moroni, Maurizio
    Munari, Davide
    Pain, Gilles
    Regalia, Nickolas
    Sartori, Luca
    Vultaggio, Stefania
    Dondio, Giulio
    Gagliardi, Stefania
    Minucci, Saverio
    Mercurio, Ciro
    Varasi, Mario
    JOURNAL OF MEDICINAL CHEMISTRY, 2010, 53 (02) : 822 - 839