Peripheral Blood Progenitor Cell Mobilization for Autologous and Allogeneic Hematopoietic Cell Transplantation: Guidelines from the American Society for Blood and Marrow Transplantation

被引:168
作者
Duong, Hien K. [1 ]
Savani, Bipin N. [2 ]
Copelan, Ed [3 ]
Devine, Steven [4 ]
Costa, Luciano J. [5 ]
Wingard, John R. [6 ]
Shaughnessy, Paul [7 ]
Majhail, Navneet [1 ]
Perales, Miguel-Angel [8 ,9 ]
Cutler, Corey S. [10 ]
Bensinger, William [11 ]
Litzow, Mark R. [12 ]
Mohty, Mohamad [13 ]
Champlin, Richard E. [14 ]
Leather, Helen [6 ]
Giralt, Sergio [8 ,9 ]
Carpenter, Paul A. [11 ]
机构
[1] Cleveland Clin Fdn, Blood & Marrow Transplant Program, Dept Blood & Marrow Transplant, Cleveland, OH 44195 USA
[2] Vanderbilt Univ, Med Ctr, Div Hematol & Oncol, Nashville, TN USA
[3] Carolinas HealthCare Syst, Levine Canc Inst, Dept Hematol Oncol & Blood Disorders, Charlotte, NC USA
[4] Ohio State Univ, Dept Internal Med, Div Hematol, Columbus, OH 43210 USA
[5] Med Univ S Carolina, Dept Med, Div Hematol & Oncol, Charleston, SC 29425 USA
[6] Univ Florida, Hlth Canc Ctr, Div Hematol Oncol, Gainesville, FL USA
[7] Texas Transplant Inst, Dept Adult Bone Marrow Transplant, San Antonio, TX USA
[8] Mem Sloan Kettering Canc Ctr, Dept Med, Adult Bone Marrow Transplantat Serv, New York, NY 10021 USA
[9] Weill Cornell Med Coll, New York, NY USA
[10] Dana Farber Canc Inst, Dept Hematol Oncol, Boston, MA 02115 USA
[11] Fred Hutchinson Canc Res Ctr, Div Clin Res, Seattle, WA 98104 USA
[12] Mayo Clin, Div Palliat Med, Div Hematol, Rochester, MN USA
[13] St Antoine Hosp, Dept Haematol, Paris, France
[14] Univ Texas MD Anderson Canc Ctr, Dept Stem Cell Transplantat, Houston, TX 77030 USA
关键词
Peripheral blood; Progenitor cell mobilization; Hematopoietic transplantation; COLONY-STIMULATING FACTOR; LARGE-VOLUME LEUKAPHERESIS; VERSUS-HOST-DISEASE; NON-HODGKINS-LYMPHOMA; FACTOR G-CSF; PLUS G-CSF; STEM-CELLS; MULTIPLE-MYELOMA; PEDIATRIC-PATIENTS; NORMAL DONORS;
D O I
10.1016/j.bbmt.2014.05.003
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Peripheral blood progenitor cell mobilization practices vary significantly among institutions. Effective mobilization regimens include growth factor alone, chemotherapy and growth factor combined, and, more recently, incorporation of plerixafor with either approach. Many institutions have developed algorithms to improve stem cell mobilization success rates and cost-effectiveness. However, an optimal stem cell mobilization regimen has not been defined. Practical guidelines are needed to address important clinical questions, including which growth factor is optimal, what chemotherapy and dose is most effective, and when to initiate leukapheresis. We present recommendations, based on a comprehensive review of the literature, from the American Society of Blood and Marrow Transplantation. (C) 2014 American Society for Blood and Marrow Transplantation.
引用
收藏
页码:1262 / 1273
页数:12
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