A highly sensitive ratiometric fluorescent probe with a large emission shift for imaging endogenous cysteine in living cells

被引：91
作者：
Zhu, Baocun [1 ]
Guo, Bingpeng [1 ]
Zhao, Yunzhou [1 ]
Zhang, Bing [1 ]
Du, Bin [1 ]
机构：
[1] Univ Jinan, Shandong Prov Engn Technol Res Ctr Ecol Carbon Si, Sch Resources & Environm, Jinan 250022, Peoples R China
来源：
BIOSENSORS & BIOELECTRONICS | 2014年 / 55卷
基金：
中国国家自然科学基金;
关键词：
Ratiometric fluorescent probe; Hydroxynaphthalimide; Large emission shift; Cysteine; Bioimaging; CHEMODOSIMETER; HOMOCYSTEINE; QUANTIFICATION; THIOLS;
D O I：
10.1016/j.bios.2013.11.068
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
A new design strategy for the construction of ratiometric fluorescent probe with a large emission shift was developed. Based on this strategy, a highly selective and sensitive calorimetric and ratiometic fluorescent probe for cysteine (Cys) with a 117 nm red-shifted emission was synthesized and applied to the ratiometric imaging of endogenous Cys in living cells. (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码：72 / 75
页数：4
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