Why internal weights should be avoided (not only) in MR-Egger regression

被引：28

作者：

Hartwig, Fernando Pires ^{[1
,2
]}

Davies, Neil Martin ^{[2
,3
]}

机构：

[1] Univ Fed Pelotas, Postgrad Program Epidemiol, R Gomes Carneiro 1, BR-96020220 Pelotas, RS, Brazil

[2] Univ Bristol, Med Res Council Integrat Epidemiol Unit, Bristol, Avon, England

[3] Univ Bristol, Sch Social & Community Med, Bristol, Avon, England

来源：

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY | 2016年 / 45卷 / 05期

基金：

英国医学研究理事会;

关键词：

MENDELIAN RANDOMIZATION; DESIGN;

D O I：

10.1093/ije/dyw240

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

引用

页码：1676 / 1678

页数：3

共 13 条

[1] Hundreds of variants clustered in genomic loci and biological pathways affect human height [J].

Allen, Hana Lango ;

Estrada, Karol ;

Lettre, Guillaume ;

Berndt, Sonja I. ;

Weedon, Michael N. ;

Rivadeneira, Fernando ;

Willer, Cristen J. ;

Jackson, Anne U. ;

Vedantam, Sailaja ;

Raychaudhuri, Soumya ;

Ferreira, Teresa ;

Wood, Andrew R. ;

Weyant, Robert J. ;

Segre, Ayellet V. ;

Speliotes, Elizabeth K. ;

Wheeler, Eleanor ;

Soranzo, Nicole ;

Park, Ju-Hyun ;

Yang, Jian ;

Gudbjartsson, Daniel ;

Heard-Costa, Nancy L. ;

Randall, Joshua C. ;

Qi, Lu ;

Smith, Albert Vernon ;

Maegi, Reedik ;

Pastinen, Tomi ;

Liang, Liming ;

Heid, Iris M. ;

Luan, Jian'an ;

Thorleifsson, Gudmar ;

Winkler, Thomas W. ;

Goddard, Michael E. ;

Lo, Ken Sin ;

Palmer, Cameron ;

Workalemahu, Tsegaselassie ;

Aulchenko, Yurii S. ;

Johansson, Asa ;

Zillikens, M. Carola ;

Feitosa, Mary F. ;

Esko, Tonu ;

Johnson, Toby ;

Ketkar, Shamika ;

Kraft, Peter ;

Mangino, Massimo ;

Prokopenko, Inga ;

Absher, Devin ;

Albrecht, Eva ;

Ernst, Florian ;

Glazer, Nicole L. ;

Hayward, Caroline .

NATURE, 2010, 467 (7317) :832-838

[2] Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator [J].

Bowden, Jack ;

Smith, George Davey ;

Haycock, Philip C. ;

Burgess, Stephen .

GENETIC EPIDEMIOLOGY, 2016, 40 (04) :304-314

[3] Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression [J].

Bowden, Jack ;

Smith, George Davey ;

Burgess, Stephen .

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2015, 44 (02) :512-525

[4] Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors [J].

Burgess, Stephen ;

Scott, Robert A. ;

Timpson, Nicholas J. ;

Smith, George Davey ;

Thompson, Simon G. .

EUROPEAN JOURNAL OF EPIDEMIOLOGY, 2015, 30 (07) :543-552

[5] Mendelian randomization: where are we now and where are we going? [J].

Burgess, Stephen ;

Timpson, Nicholas J. ;

Ebrahim, Shah ;

Smith, George Davey .

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2015, 44 (02) :379-388

[6] Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data [J].

Burgess, Stephen ;

Butterworth, Adam ;

Thompson, Simon G. .

GENETIC EPIDEMIOLOGY, 2013, 37 (07) :658-665

[7] The many weak instruments problem and Mendelian randomization [J].

Davies, Neil M. ;

Scholder, Stephanie von Hinke Kessler ;

Farbmacher, Helmut ;

Burgess, Stephen ;

Windmeijer, Frank ;

Smith, George Davey .

STATISTICS IN MEDICINE, 2015, 34 (03) :454-468

[8] Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies [J].

Haycock, Philip C. ;

Burgess, Stephen ;

Wade, Kaitlin H. ;

Bowden, Jack ;

Relton, Caroline ;

Smith, George Davey .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 2016, 103 (04) :965-978

[9] Using Mendelian randomization to investigate a possible causal relationship between adiposity and increased bone mineral density at different skeletal sites in children [J].

Kemp, John P. ;

Sayers, Adrian ;

Smith, George Davey ;

Tobias, Jonathan H. ;

Evans, David M. .

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2016, 45 (05) :1560-1572

[10] Genetic studies of body mass index yield new insights for obesity biology [J].

Locke, Adam E. ;

Kahali, Bratati ;

Berndt, Sonja I. ;

Justice, Anne E. ;

Pers, Tune H. ;

Day, Felix R. ;

Powell, Corey ;

Vedantam, Sailaja ;

Buchkovich, Martin L. ;

Yang, Jian ;

Croteau-Chonka, Damien C. ;

Esko, Tonu ;

Fall, Tove ;

Ferreira, Teresa ;

Gustafsson, Stefan ;

Kutalik, Zoltan ;

Luan, Jian'an ;

Maegi, Reedik ;

Randall, Joshua C. ;

Winkler, Thomas W. ;

Wood, Andrew R. ;

Workalemahu, Tsegaselassie ;

Faul, Jessica D. ;

Smith, Jennifer A. ;

Zhao, Jing Hua ;

Zhao, Wei ;

Chen, Jin ;

Fehrmann, Rudolf ;

Hedman, Asa K. ;

Karjalainen, Juha ;

Schmidt, Ellen M. ;

Absher, Devin ;

Amin, Najaf ;

Anderson, Denise ;

Beekman, Marian ;

Bolton, Jennifer L. ;

Bragg-Gresham, L. ;

Buyske, Steven ;

Demirkan, Ayse ;

Deng, Guohong ;

Ehret, Georg B. ;

Feenstra, Bjarke ;

Feitosa, Mary F. ;

Fischer, Krista ;

Goel, Anuj ;

Gong, Jian ;

Jackson, Anne U. ;

Kanoni, Stavroula ;

Kleber, Marcus E. ;

Kristiansson, Kati .

NATURE, 2015, 518 (7538) :197-+

← 1 2 →