Utility of neurological smears for intrasurgical brain cancer diagnostics and tumour cell percentage by DESI-MS

被引：25

作者：

Pirro, V. ^{[1
]}

Jarmusch, A. K. ^{[1
]}

Alfaro, C. M. ^{[1
]}

Hattab, E. M. ^{[2
]}

Cohen-Gadol, A. A. ^{[3
]}

Cooks, R. Graham ^{[1
]}

机构：

[1] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA

[2] Univ Louisville, Dept Pathol & Lab Med, Louisville, KY 40292 USA

[3] Indiana Univ Sch Med, Dept Neurol Sci, Indianapolis, IN 46202 USA

来源：

ANALYST | 2017年 / 142卷 / 03期

关键词：

DESORPTION ELECTROSPRAY-IONIZATION; MASS-SPECTROMETRIC ANALYSIS; TISSUE-SECTIONS; METABOLITE; SPECIMENS; PROFILES;

D O I：

10.1039/c6an02645a

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Analysis of neurological smears by desorption electrospray ionization mass spectrometry (DESI-MS) is an emerging diagnostic strategy for intraoperative consultation in brain tumor resection. DESI-MS allows rapid sampling while providing accurate diagnostic information. We assess the chemical homogeneity of neurological smears using DESI-MS imaging and the quality of rapid DESI-MS diagnosis.

引用

收藏

页码：449 / 454

页数：6

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