An approach to the inverse folding problem based on the multiple structural alignment

被引：0
|
作者：
Sunyaev, SR [1 ]
Eisenhaber, F [1 ]
Tumanyan, VG [1 ]
机构：
[1] Russian Acad Sci, VA Engelhardt Mol Biol Inst, Moscow 117984, Russia
来源：
BIOFIZIKA | 1999年 / 44卷 / 04期
关键词：
protein; architecture; recognition; multiple alignment;
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
A new approach to the inverse folding problem is proposed, which is based on the analysis of multiple structural alignments of protein families. The incorporation of multiple structure information allows one to take into account the variability of structural characteristics amongst protein structures of the same fold. The new method was tested on two highly populated structural families.
引用
收藏
页码：620 / 623
页数：4
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