Recurrent Clostridioides difficile infection: Recognition, management, prevention

被引：18

作者：

Tsigrelis, Constantine ^{[1
,2
]}

机构：

[1] Cleveland Clin, Dept Infect Dis, G21,9500 Euclid Ave, Cleveland, OH 44195 USA

[2] Case Western Reserve Univ, Lerner Coll Med, Cleveland Clin, Cleveland, OH 44106 USA

来源：

CLEVELAND CLINIC JOURNAL OF MEDICINE | 2020年 / 87卷 / 06期

关键词：

FECAL MICROBIOTA TRANSPLANTATION; CLINICAL-PRACTICE GUIDELINES; HEALTH-CARE EPIDEMIOLOGY; INTESTINAL MICROBIOME; DISEASES SOCIETY; VANCOMYCIN; BEZLOTOXUMAB; UPDATE; ADULTS; FIDAXOMICIN;

D O I：

10.3949/ccjm.87gr.20001

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Clostridioides difficile infection (CDI) is the most common cause of diarrhea in hospitalized patients and results in substantial morbidity, mortality, and costs. Its clinical management, primarily with antibiotics, is often complicated by recurrent episodes. These recurrent CDI episodes are thought to be caused by antibiotic disruption of colonic microbiota and usually occur within 4 weeks of completing antibiotic therapy. The risk of recurrent CDI increases after the first episode, creating a need for management strategies to diagnose, treat, and prevent these complications.

引用

页码：347 / 359

页数：13

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