Immunohistochemical Analysis of Active Caspase-3 Expression in Structures of Neonatal Brain

被引：6
|
作者：
Lanshakov, D. A. [1 ,2 ]
Bulygina, V. V. [1 ]
Romanova, I. V. [3 ]
Dygalo, N. N. [1 ,2 ]
机构：
[1] Russian Acad Sci, Inst Cytol & Genet, Lab Funct Neurogen, Siberian Div, Novosibirsk 630090, Russia
[2] Novosibirsk State Univ, Novosibirsk, Russia
[3] Russian Acad Sci, Inst Evolut Biochem & Physiol, St Petersburg 196140, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2009年 / 147卷 / 05期
基金：
俄罗斯基础研究基金会;
关键词：
active caspase-3; brain; hippocampus; ontogeny; CENTRAL-NERVOUS-SYSTEM; MESSENGER-RNA; DNA FRAGMENTATION; APOPTOSIS;
D O I：
10.1007/s10517-009-0563-6
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The hippocampal fields of neonatal rats differ by the level of active caspase-3: dentate gyrus >CA3>CA1>CA2. In the dentate gyrus it was 70% of its maximum value in the cortex, while in CA2 it corresponded to the minimum level in the brain stem. Taking into account the role of caspase-3 in apoptosis, these differences can indicate different intensity of programmed cell death in different fields of the forming hippocampus.
引用
收藏
页码：635 / 638
页数：4
相关论文
共 50 条
  • [1] Immunohistochemical Analysis of Active Caspase-3 Expression in Structures of Neonatal Brain
    D. A. Lanshakov
    V. V. Bulygina
    I. V. Romanova
    N. N. Dygalo
    Bulletin of Experimental Biology and Medicine, 2009, 147 : 635 - 638
  • [2] Effects of Dexamethasone on the Development of Neonatal Rats and Level of Active Caspase-3 in Brain Cortex
    Menshanov, P. N.
    Muzyka, V. V.
    Dygalo, N. N.
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2012, 153 (04) : 478 - 480
  • [3] Effects of Dexamethasone on the Development of Neonatal Rats and Level of Active Caspase-3 in Brain Cortex
    P. N. Menshanov
    V. V. Muzyka
    N. N. Dygalo
    Bulletin of Experimental Biology and Medicine, 2012, 153 : 478 - 480
  • [4] Effects of hypoxia ischemia on caspase-3 expression and neuronal apoptosis in the brain of neonatal mice
    Deng, Changbo
    Li, Juan
    Li, Luyi
    Sun, Fengjie
    Xie, Jiqing
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 17 (06) : 4517 - 4521
  • [5] Immunohistochemical expression of activated caspase-3 in human myocardial infarction
    Zidar, N
    Dolenc-Strazar, Z
    Jeruc, J
    Stajer, D
    EUROPEAN HEART JOURNAL, 2004, 25 : 375 - 375
  • [6] Immunohistochemical expression of activated caspase-3 in human myocardial infarction
    Zidar, N
    Dolenc-Strazar, Z
    Jeruc, J
    Stajer, D
    VIRCHOWS ARCHIV, 2006, 448 (01) : 75 - 79
  • [7] Immunohistochemical expression of activated caspase-3 in human myocardial infarction
    Nina Zidar
    Zvezdana Dolenc-Stražar
    Jera Jeruc
    Dušan Štajer
    Virchows Archiv, 2006, 448 : 75 - 79
  • [8] Active caspase-3 expression in healthy lens epithelium
    Zadeh, N. Talebi
    Yu, Z.
    Kronschlager, M.
    Soderberg, P.
    ACTA OPHTHALMOLOGICA, 2013, 91
  • [9] Caspase-3 and Bcl-2 expression in glioblastoma An immunohistochemical study
    Tirapelli, Luis Fernando
    Nasser Andre Bolini, Paulo Henrique
    da Cunha Tirapelli, Daniela Pretti
    Peria, Fernanda Maris
    Paixao Becker, Aline Nazareth
    Saggioro, Fabiano Pinto
    Carlotti Junior, Carlos Gilberto
    ARQUIVOS DE NEURO-PSIQUIATRIA, 2010, 68 (04) : 603 - 607
  • [10] The interrelationship between BDNF and its precursor and the level of active caspase-3 in the brain regions of neonatal rats
    Muzyka, V. V.
    Men'shanov, P. N.
    Bannova, A. V.
    Dygalo, N. N.
    NEUROCHEMICAL JOURNAL, 2012, 6 (04) : 260 - 264
12345