Measurement of daily sodium excretion in patients with chronic kidney disease; special reference to the difference between the amount measured from 24h collected urine sample and the estimated amount from a spot urine

被引：6
作者：
Amano, Hoichi [1 ,2 ]
Kobayashi, Seiji [1 ,3 ]
Terawaki, Hiroyuki [4 ]
Ogura, Makoto [1 ]
Kawaguchi, Yoshindo [1 ]
Yokoo, Takashi [1 ]
机构：
[1] Jikei Univ, Sch Med, Dept Internal Med, Div Nephrol & Hypertens, Tokyo, Japan
[2] Teikyo Univ, Grad Sch Publ Hlth, Tokyo, Japan
[3] Nippon Med Sch, Grad Sch Med, Dept Allergy & Rheumatol, Tokyo, Japan
[4] Teikyo Univ, Chiba Med Ctr, Sch Med, Dept Internal Med, Ichihara, Chiba, Japan
来源：
RENAL FAILURE | 2018年 / 40卷 / 01期
关键词：
CKD; salt intake; sodium excretion; a spot urine sample; 24-hour collected urine sample; BLOOD-PRESSURE; POTASSIUM EXCRETION; CARDIOVASCULAR EVENTS; HYPERTENSION; RHYTHM;
D O I：
10.1080/0886022X.2018.1456452
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
It is important to grasp a patient's daily sodium intake in the management of chronic kidney disease, as sodium intake is widely recommended at 6g/day or less. There are multiple equations widely known for estimating the daily sodium excretion from a spot urine sample, but these are aimed at healthy people. There are few reports that validate equations in patients with chronic kidney disease. The purpose of this study is to evaluate whether the amount of measured daily sodium excretion from a sample collected for 24-h urine (24HU) is equal to that of using an equation from a spot urine sample (SU) in patients with chronic kidney disease. One hundred sixty-two patients with chronic kidney disease from Kanagawa Prefecture Shiomidai Hospital, Japan and the Jikei University Kashiwa Hospital, Japan participated in the study. Daily sodium excretion was measured from 24HU and compared with it from SU by using the formula according to Tanaka etal. Sodium excretion by 24HU was 2744mg/day and estimating daily sodium excretion from SU was 3315mg/day. The coefficient of determination was 0.17 (p<.001) in multivariate regression analysis. The coefficient of determination was extremely low. Thus, there is a considerable difference between the amount of sodium excretion calculated from a 24HU and that from a SU in patients with chronic kidney disease.
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收藏
页码：238 / 242
页数：5
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