Reinterpretation of histology of proximal colon polyps called hyperplastic in 2001

被引：124
作者：
Khalid, Omer [1 ]
Radaideh, Sofyan [1 ]
Cummings, Oscar W. [2 ]
O'Brien, Michael J. [3 ]
Goldblum, John R. [4 ]
Rex, Douglas K. [5 ]
机构：
[1] Indiana Univ, Med Ctr, Dept Med, Indianapolis, IN 46202 USA
[2] Indiana Univ, Med Ctr, Dept Pathol, Indianapolis, IN 46202 USA
[3] Boston Univ, Med Ctr, Dept Anat Pathol, Boston, MA 02118 USA
[4] Cleveland Clin, Dept Anat Pathol, Cleveland, OH 44195 USA
[5] Indiana Univ, Med Ctr, Div Gastroenterol Hepatol, Indianapolis, IN 46202 USA
来源：
WORLD JOURNAL OF GASTROENTEROLOGY | 2009年 / 15卷 / 30期
关键词：
Colonoscopy; Colorectal polyps; Hyperplastic polyps; Inter-observer variability; Serrated adenomas; Sessile serrated polyps; SERRATED COLORECTAL POLYPS; LARGE-INTESTINE; ADENOMAS; COLONOSCOPY; REAPPRAISAL; MUTATIONS; LESIONS; CANCER; GENDER; BRAF;
D O I：
10.3748/wjg.15.3767
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
AIM: To evaluate how proximal colon polyps interpreted as hyperplastic polyps in 2001 would be interpreted by expert pathologists in 2007. METHODS: Forty consecutive proximal colon polyps >= 5 mm in size, removed in 2001, and originally interpreted as hyperplastic polyps by general pathologists at Indiana University, were reviewed in 2007 by 3 GI pathologists. RESULTS: The gastrointestinal (GI) pathologists interpreted 85%, 43% and 30% of the polyps as sessile serrated polyps (sessile serrated adenomas). The overall Kappa was 0.16. When diagnoses were compared in pairs, Kappa values were 0.38 and 0.25 (fair agreement) and 0.14 (slight agreement). CONCLUSION: Many polyps interpreted as hyperplastic in 2001 were considered sessile serrated lesions by GI pathologists in 2007, but there is substantial inter-observer variation amongst GI pathologists. (C) 2009 The WJG Press and Baishideng. All rights reserved.
引用
收藏
页码：3767 / 3770
页数：4
相关论文
共 20 条
[1]  
[Anonymous], 2000, WHO CLASSIFICATION T
[2]   Endoscopist can be more powerful than age and male gender in predicting adenoma detection at colonoscopy [J].
Chen, Shawn C. ;
Rex, Douglas K. .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2007, 102 (04) :856-861
[3]   Serrated mucosal lesions of the colorectum [J].
Cunningham, KS ;
Riddell, RH .
CURRENT OPINION IN GASTROENTEROLOGY, 2006, 22 (01) :48-53
[4]   A multinational, Internet-based assessment of observer variability in the diagnosis of serrated colorectal polyps [J].
Glatz, Katharina ;
Pritt, Bobbi ;
Glatz, Dieter ;
Hartmann, Arndt ;
O'Brien, Michael J. ;
Blaszyk, Hagen .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2007, 127 (06) :938-945
[5]   Clinical significance of (Sessile) serrated adenomas - Another piece of the puzzle [J].
Goldstein, NS .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2005, 123 (03) :329-330
[6]   Demographic and pathological characteristics of serrated polyps of colorectum [J].
Higuchi, T ;
Sugihara, K ;
Jass, JR .
HISTOPATHOLOGY, 2005, 47 (01) :32-40
[7]   The risk of metachronous neoplasia in patients with serrated adenoma [J].
Lazarus, R ;
Junttila, OE ;
Karttunen, TJ ;
Mäkinen, MJ .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2005, 123 (03) :349-359
[8]   Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: A joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology [J].
Levin, Bernard ;
Lieberman, David A. ;
McFarland, Beth ;
Andrews, Kimberly S. ;
Brooks, Durado ;
Bond, John ;
Dash, Chiranjeev ;
Giardiello, Francis M. ;
Glick, Seth ;
Johnson, David ;
Johnson, C. Daniel ;
Levin, Theodore R. ;
Pickhardt, Perry J. ;
Rex, Douglas K. ;
Smith, Robert A. ;
Thorson, Alan ;
Winawer, Sidney J. .
GASTROENTEROLOGY, 2008, 134 (05) :1570-1595
[9]   Colorectal serrated adenocarcinoma [J].
Makinen, M. J. .
HISTOPATHOLOGY, 2007, 50 (01) :131-150
[10]   Serrated colorectal polyps: Emerging evidence suggests the need for a reappraisal [J].
Montgomery, E .
ADVANCES IN ANATOMIC PATHOLOGY, 2004, 11 (03) :143-149
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