Reinterpretation of histology of proximal colon polyps called hyperplastic in 2001

被引:122
作者
Khalid, Omer [1 ]
Radaideh, Sofyan [1 ]
Cummings, Oscar W. [2 ]
O'Brien, Michael J. [3 ]
Goldblum, John R. [4 ]
Rex, Douglas K. [5 ]
机构
[1] Indiana Univ, Med Ctr, Dept Med, Indianapolis, IN 46202 USA
[2] Indiana Univ, Med Ctr, Dept Pathol, Indianapolis, IN 46202 USA
[3] Boston Univ, Med Ctr, Dept Anat Pathol, Boston, MA 02118 USA
[4] Cleveland Clin, Dept Anat Pathol, Cleveland, OH 44195 USA
[5] Indiana Univ, Med Ctr, Div Gastroenterol Hepatol, Indianapolis, IN 46202 USA
关键词
Colonoscopy; Colorectal polyps; Hyperplastic polyps; Inter-observer variability; Serrated adenomas; Sessile serrated polyps; SERRATED COLORECTAL POLYPS; LARGE-INTESTINE; ADENOMAS; COLONOSCOPY; REAPPRAISAL; MUTATIONS; LESIONS; CANCER; GENDER; BRAF;
D O I
10.3748/wjg.15.3767
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
AIM: To evaluate how proximal colon polyps interpreted as hyperplastic polyps in 2001 would be interpreted by expert pathologists in 2007. METHODS: Forty consecutive proximal colon polyps >= 5 mm in size, removed in 2001, and originally interpreted as hyperplastic polyps by general pathologists at Indiana University, were reviewed in 2007 by 3 GI pathologists. RESULTS: The gastrointestinal (GI) pathologists interpreted 85%, 43% and 30% of the polyps as sessile serrated polyps (sessile serrated adenomas). The overall Kappa was 0.16. When diagnoses were compared in pairs, Kappa values were 0.38 and 0.25 (fair agreement) and 0.14 (slight agreement). CONCLUSION: Many polyps interpreted as hyperplastic in 2001 were considered sessile serrated lesions by GI pathologists in 2007, but there is substantial inter-observer variation amongst GI pathologists. (C) 2009 The WJG Press and Baishideng. All rights reserved.
引用
收藏
页码:3767 / 3770
页数:4
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