Spirocycles, including spirocyclic ethers, occur frequently in natural products and pharmaceutically active substances. Accordingly, synthetic methodologies utilized for the preparation of such compounds are of broad interest. The present review focuses on the general synthetic approaches that have been utilized for the construction of spirocyclic ethers during the past two decades.
机构:
Tokyo Inst Technol, Grad Sch Sci & Engn, Dept Appl Chem, Meguro Ku, Tokyo 1528552, JapanTokyo Inst Technol, Grad Sch Sci & Engn, Dept Appl Chem, Meguro Ku, Tokyo 1528552, Japan
机构:
Tokyo Inst Technol, Grad Sch Sci & Engn, Dept Appl Chem, Meguro Ku, Tokyo 1528552, JapanTokyo Inst Technol, Grad Sch Sci & Engn, Dept Appl Chem, Meguro Ku, Tokyo 1528552, Japan