Current issues in chronic graft-versus-host disease

被引：287

作者：

Socie, Gerard ^{[1
,2
,3
]}

Ritz, Jerome ^{[4
,5
]}

机构：

[1] Hop St Louis, AP HP, Div Hematol Immunol Oncol, F-75475 Paris 10, France

[2] Univ Paris 07, Paris, France

[3] INSERM, U1160, Team GVHD & Allogene Transplantat, Paris, France

[4] Dana Farber Canc Inst, Boston, MA 02115 USA

[5] Harvard Univ, Sch Med, Boston, MA USA

来源：

BLOOD | 2014年 / 124卷 / 03期

基金：

美国国家卫生研究院;

关键词：

CONSENSUS DEVELOPMENT PROJECT; STEM-CELL TRANSPLANTATION; MINOR HISTOCOMPATIBILITY ANTIGEN; REGULATORY T-CELLS; LONG-TERM SURVIVAL; CHRONIC GVHD; CLINICAL-TRIALS; B-CELL; RANDOMIZED-TRIAL; EXTRACORPOREAL PHOTOCHEMOTHERAPY;

D O I：

10.1182/blood-2014-01-514752

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Chronic graft-versus-host disease (GVHD) is a frequent and potentially life-threatening complication of allogeneic hematopoietic stem cell transplantation. Increased transplantation of older patients and the more frequent use of unrelated donors has led to increased numbers of patients with this painful complication. Recent advances have been made in understanding the pathophysiology of chronic GVHD and in establishing precise criteria for diagnosis and classification of disease manifestations. These advances will hopefully pave the way for improving both the prophylaxis and treatment of chronic GVHD.

引用

页码：374 / 384

页数：11

共 105 条

[1] Performance of a new clinical grading system for chronic graft-versus-host disease: a multicenter study [J].

Akpek, G ;

Lee, SJ ;

Flowers, ME ;

Pavletic, SZ ;

Arora, M ;

Lee, S ;

Piantadosi, S ;

Guthrie, KA ;

Lynch, JC ;

Takatu, A ;

Horowitz, MM ;

Antin, JH ;

Weisdorf, DJ ;

Martin, PJ ;

Vogelsang, GB .

BLOOD, 2003, 102 (03) :802-809

[2] BCR Hyper-Responsiveness In B Cells From Patients With Chronic Gvhd Is Blocked With The Syk Inhibitor R406 [J].

Allen, Jessica L. ;

Tata, Prasanthi V. ;

Wooten, Jenna ;

Fore, Matthew S. ;

Deal, Allison M. ;

Sharf, Andrew ;

Hoffert, Todd ;

Roehrs, Philip A. ;

Armistead, Paul M. ;

Coghill, James ;

Wood, William A. ;

Shea, Thomas C. ;

Serody, Jonathan ;

Richards, Kristy L. ;

Jagasia, Madan ;

Lee, Stephanie J. ;

Rowe, Krista ;

Rizzieri, David ;

Horwitz, Mitchell E. ;

Chao, Nelson J. ;

Sarantopoulos, Stefanie .

BLOOD, 2013, 122 (21)

[3]

Apkek G, 2009, CHRONIC GRAFT VERSUS, V1, P70

[4] Prophylactic rituximab after allogeneic transplantation decreases B-cell alloimmunity with low chronic GVHD incidence [J].

Arai, Sally ;

Sahaf, Bita ;

Narasimhan, Balasubramanian ;

Chen, George L. ;

Jones, Carol D. ;

Lowsky, Robert ;

Shizuru, Judith A. ;

Johnston, Laura J. ;

Laport, Ginna G. ;

Weng, Wen-Kai ;

Benjamin, Jonathan E. ;

Schaenman, Joanna ;

Brown, Janice ;

Ramirez, Jessica ;

Zehnder, James L. ;

Negrin, Robert S. ;

Miklos, David B. .

BLOOD, 2012, 119 (25) :6145-6154

[5] Global and organ-specific chronic graft-versus-host disease severity according to the 2005 NIH Consensus Criteria [J].

Arai, Sally ;

Jagasia, Madan ;

Storer, Barry ;

Chai, Xiaoyu ;

Pidala, Joseph ;

Cutler, Corey ;

Arora, Mukta ;

Weisdorf, Daniel J. ;

Flowers, Mary E. D. ;

Martin, Paul J. ;

Palmer, Jeanne ;

Jacobsohn, David ;

Pavletic, Steven Z. ;

Vogelsang, Georgia B. ;

Lee, Stephanie J. .

BLOOD, 2011, 118 (15) :4242-4249

[6]

Arai S, 2009, CHRONIC GRAFT VERSUS HOST DISEASE: INTERDISCIPLINARY MANAGEMENT, P46, DOI 10.1017/CBO9780511576751.006

[7] Randomized clinical trial of thalidomide, cyclosporine, and prednisone versus cyclosporine and prednisone as initial therapy for chronic graft-versus-host disease [J].

Arora, M ;

Wagner, JE ;

Davies, SM ;

Blazar, BR ;

Defor, T ;

Enright, H ;

Miller, WF ;

Weisdorf, DJ .

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2001, 7 (05) :265-273

[8] Chronic GVHD risk score: a Center for International Blood and Marrow Transplant Research analysis [J].

Arora, Mukta ;

Klein, John P. ;

Weisdorf, Daniel J. ;

Hassebroek, Anna ;

Flowers, Mary E. D. ;

Cutler, Corey S. ;

Urbano-Ispizua, Alvaro ;

Antin, Joseph H. ;

Bolwell, Brian J. ;

Boyiadzis, Michael ;

Cahn, Jean-Yves ;

Cairo, Mitchell S. ;

Isola, Luis ;

Jacobsohn, David A. ;

Jagasia, Madan ;

Klumpp, Thomas R. ;

Lee, Stephanie J. ;

Petersdorf, Effie W. ;

Santarone, Stella ;

Gale, Robert Peter ;

Schouten, Harry C. ;

Spellman, Stephen ;

Wingard, John R. ;

Horowitz, Mary M. ;

Pavletic, Steven Z. .

BLOOD, 2011, 117 (24) :6714-6720

[9] Thymoglobulin prevents chronic graft-versus-host disease, chronic lung dysfunction, and late transplant-related mortality: Long-term follow-up of a randomized trial in patients undergoing unrelated donor transplantation [J].

Bacigalupo, A ;

Lamparelli, T ;

Barisione, G ;

Bruzzi, P ;

Guidi, S ;

Alessandrino, PE ;

di Bartolomeo, P ;

Oneto, R ;

Bruno, B ;

Sacchi, N ;

van Lint, MT ;

Bosi, A .

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2006, 12 (05) :560-565

[10] Antithymocyte globulin for graft-versus-host disease prophylaxis in transplants from unrelated donors: 2 randomized studies from Gruppo Italiano Trapianti Midollo Osseo (GITMO) [J].

Bacigalupo, A ;

Lamparelli, T ;

Bruzzi, P ;

Guidi, S ;

Alessandrino, PE ;

di Bartolomeo, P ;

Oneto, R ;

Bruno, B ;

Barbanti, M ;

Sacchi, N ;

Van Lint, MT ;

Bosi, A .

BLOOD, 2001, 98 (10) :2942-2947

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