Revisiting guidelines for integration of flow cytometry results in the WHO classification of myelodysplastic syndromes-proposal from the International/European LeukemiaNet Working Group for Flow Cytometry in MDS

被引：106

作者：

Porwit, A. ^{[1
]}

van de Loosdrecht, A. A. ^{[2
]}

Bettelheim, P. ^{[3
]}

Brodersen, L. Eidenschink ^{[4
]}

Burbury, K. ^{[5
]}

Cremers, E. ^{[2
]}

Della Porta, M. G. ^{[6
,7
]}

Ireland, R. ^{[8
]}

Johansson, U. ^{[9
]}

Matarraz, S. ^{[10
,11
]}

Ogata, K. ^{[12
]}

Orfao, A. ^{[10
,11
]}

Preijers, F. ^{[13
]}

Psarra, K. ^{[14
]}

Subira, D. ^{[15
]}

Valent, P. ^{[16
,17
]}

van der Velden, V. H. J. ^{[18
]}

Wells, D. ^{[4
]}

Westers, T. M. ^{[2
]}

Kern, W. ^{[19
]}

Bene, M. C. ^{[20
]}

机构：

[1] Univ Toronto, Toronto Gen Hosp, Univ Hlth Network, Dept Pathobiol & Lab Med, Toronto, ON M5G 1L7, Canada

[2] Vrije Univ Amsterdam Med Ctr, Canc Ctr Amsterdam, Dept Hematol, Amsterdam, Netherlands

[3] Elisabethinen Hosp, Dept Med 1, Linz, Austria

[4] HematoLogics Inc, Seattle, WA USA

[5] Peter MacCallum Canc Ctr, Div Canc Med, Melbourne, Vic, Australia

[6] Fdn IRCCS Policlin San Matteo, Dept Hematol & Oncol, Pavia, Italy

[7] Univ Pavia, I-27100 Pavia, Italy

[8] Kings Coll Hosp London, London, England

[9] Univ Hosp, Bristol, Avon, England

[10] Univ Salamanca, Inst Biol Celular & Mol Canc CSIC USAL IBSAL, Ctr Invest Canc, Serv Cent Citometria, E-37008 Salamanca, Spain

[11] Univ Salamanca, Dept Med, E-37008 Salamanca, Spain

[12] Metropolitan Res Ctr Blood Disorders MRC JAPAN, Chofu, Tokyo, Japan

[13] St Radboud Univ Med Ctr, Dept Hematol, Nijmegen, Netherlands

[14] Evangelismos Med Ctr, Dept Immunol Histocompatibil, Athens, Greece

[15] Hosp Univ Guadalajara, Dept Hematol, Guadalajara, Spain

[16] Med Univ Vienna, Dept Internal Med 1, Div Hematol & Hemostaseol, Vienna, Austria

[17] Med Univ Vienna, Ludwig Boltzmann Cluster Oncol, Vienna, Austria

[18] Univ Med Ctr Rotterdam, Erasmus MC, Dept Immunol, Rotterdam, Netherlands

[19] MLL Munich Leukemia Lab, Munich, Germany

[20] CHU Nantes, Serv Hematol Biol, F-44035 Nantes 01, France

来源：

LEUKEMIA | 2014年 / 28卷 / 09期

关键词：

SCORING SYSTEM; BONE-MARROW; LOW-GRADE; DIAGNOSTIC APPLICATION; MULTICENTER VALIDATION; REFRACTORY CYTOPENIA; ERYTHROID DYSPLASIA; ANTIGEN-EXPRESSION; BLAST CELLS; UTILITY;

D O I：

10.1038/leu.2014.191

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Definite progress has been made in the exploration of myelodysplastic syndromes (MDS) by flow cytometry (FCM) since the publication of the World Health Organization 2008 classification of myeloid neoplasms. An international working party initiated within the European LeukemiaNet and extended to include members from Australia, Canada, Japan, Taiwan and the United States has, through several workshops, developed and subsequently published consensus recommendations. The latter deal with preanalytical precautions, and propose small and large panels, which allow evaluating immunophenotypic anomalies and calculating myelodysplasia scores. The current paper provides guidelines that strongly recommend the integration of FCM data with other diagnostic tools in the diagnostic work-up of MDS.

引用

页码：1793 / 1798

页数：6

共 62 条

[1] Applicability of a reproducible flow cytometry scoring system in the diagnosis of refractory cytopenia of childhood [J].

Aalbers, A. M. ;

van den Heuvel-Eibrink, M. M. ;

de Haas, V. ;

te Marvelde, J. G. ;

de Jong, A. X. ;

van der Burg, M. ;

Dworzak, M. ;

Hasle, H. ;

Locatelli, F. ;

De Moerloose, B. ;

Schmugge, M. ;

Stary, J. ;

Zecca, M. ;

Zwaan, C. M. ;

van de Loosdrecht, A. A. ;

van Dongen, J. J. M. ;

Niemeyer, C. M. ;

van der Velden, V. H. J. .

LEUKEMIA, 2013, 27 (09) :1923-1925

[2] Absence of aberrant myeloid progenitors by flow cytometry is associated with favorable response to azacitidine in higher risk myelodysplastic syndromes [J].

Alhan, Canan ;

Westers, Theresia M. ;

van der Helm, Lieke H. ;

Eeltink, Corien ;

Huls, Gerwin ;

Witte, Birgit I. ;

Buchi, Francesca ;

Santini, Valeria ;

Ossenkoppele, Gert J. ;

van de Loosdrecht, Arjan A. .

CYTOMETRY PART B-CLINICAL CYTOMETRY, 2014, 86 (03) :207-215

[3] Single Nucleotide Polymorphism Array Karyotyping: A Diagnostic and Prognostic Tool in Myelodysplastic Syndromes with Unsuccessful Conventional Cytogenetic Testing [J].

Arenillas, Leonor ;

Mallo, Mar ;

Ramos, Fernando ;

Guinta, Kathryn ;

Barragan, Eva ;

Lumbreras, Eva ;

Larrayoz, Maria-Jose ;

De Paz, Raquel ;

Tormo, Mar ;

Abaigar, Maria ;

Pedro, Carme ;

Cervera, Jose ;

Such, Esperanza ;

Jose Calasanz, Maria ;

Diez-Campelo, Maria ;

Sanz, Guillermo F. ;

Maria Hernandez, Jesus ;

Luno, Elisa ;

Saumell, Silvia ;

Maciejewski, Jaroslaw ;

Florensa, Lourdes ;

Sole, Francesc .

GENES CHROMOSOMES & CANCER, 2013, 52 (12) :1167-1177

[4] Four- and Five-Color Flow Cytometry Analysis of Leukocyte Differentiation Pathways in Normal Bone Marrow: A Reference Document Based on a Systematic Approach by the GTLLF and GEIL [J].

Arnoulet, Christine ;

Bene, Marie C. ;

Durrieu, Francoise ;

Feuillard, Jean ;

Fossat, Chantal ;

Husson, Bernard ;

Jouault, Helene ;

Maynadie, Marc ;

Lacombe, Francis .

CYTOMETRY PART B-CLINICAL CYTOMETRY, 2010, 78B (01) :3-10

[5]

Béné MC, 2003, HAEMATOLOGICA, V88, P363

[6]

Brunning RD., 2008, WHO CLASSIFICATION T, P88

[7] Role of flow cytometry in myelodysplastic syndromes: diagnosis, classification, prognosis and response assessment [J].

Burbury, Kate L. ;

Westerman, David A. .

LEUKEMIA & LYMPHOMA, 2014, 55 (04) :749-760

[8] Flow cytometry in myelodysplastic syndrome: analysis of diagnostic utility using maturation pattern-based and quantitative approaches [J].

Chopra, Anita ;

Pati, Haraprasad ;

Mahapatra, Manoranjan ;

Mishra, Pravas ;

Seth, Tulika ;

Kumar, Suman ;

Singh, Saroj ;

Pandey, Sangita ;

Kumar, Rajive .

ANNALS OF HEMATOLOGY, 2012, 91 (09) :1351-1362

[9] Flow cytometric scoring system as a diagnostic and prognostic tool in myelodysplastic syndromes [J].

Chu, Sung-Chao ;

Wang, Tso-Fu ;

Li, Chi-Cheng ;

Kao, Ruey-Ho ;

Li, Dian-Kun ;

Su, Yu-Chieh ;

Wells, Denise A. ;

Loken, Michael R. .

LEUKEMIA RESEARCH, 2011, 35 (07) :868-873

[10]

Chung JW, 2012, ANN CLIN LAB SCI, V42, P271

← 1 2 3 4 5 6 7 →